Naringenin Raw Materials Powder 480-41-1

CAS:480-41-1

MF: C15H12O5

MW:272.25

EINECS:207-550-2

Specification: 99% min Naringenin Powder

Sample: Naringenin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Naringenin Powder Usage and Synthesis.

Naringin is the glucoside of naringenin, a dihydroflavonoid, white needle-like crystals at room temperature (methanol), soluble in ethanol, ether and benzene, almost insoluble in water. Magnesium hydrochloride powder reaction is cherry red, sodium tetrahydroboron reaction is reddish purple, molish reaction negative.

In nature, it mainly originates from the flower buds of cherry blossom (PrunusyedoensisMate.), a plant of Rosaceae family, and the nucleus shells of the fruits of terracotta (Amacardi-umoccidentaleL.), a plant of Lacertaceae family. Flavonoids have similar parent nucleus structures, and most of the components have poor lipid and watersolubility and low bioavailability. By modifying their structure and introducing groups with stronger lipid orwater solubility, their lipid or water solubility can be improved, thus increasing their bioavailability. Structural modifications mainly include alkylation of hydroxyl groups, acylation, sulphonation, glycosidation and formation of metal complexes, etc.

Uses and functions of Luteolin.

Naringenin has antibacterial, anti-inflammatory, antioxidant, cough expectorant, hypolipidemic, anticancer and antitumour, antispasmodic, scavenging free radicals, preventing and treating liver disease, inhibiting platelet coagulation, anti-atherosclerosis, etc., which can be widely used in the field of medicine, food and so on.

1. Antibacterial: Staphylococcus aureus, colorectal, dysentery and typhoid fever bacillus have strong antibacterial effect. Naringenin also has a role in fungi, 1000ppm sprayed on rice can reduce the rice fungus infection 40-90%, and no toxicity to humans and livestock.

2. Anti-inflammatory: rats intraperitoneal injection of 20mg/kg per day, significantly inhibit the inflammatory process caused by the implantation of wool balls.

3. Anti-cancer: It is active against rat leukaemia L1210 and sarcoma.

4. Antispasmodic and choleretic: for the flavonoids with a strong effect. Naringenin and has a strong increase in bile secretion of experimental animals.

Pharmacological action of Naringenin Raw.

Naringenin is a flavonoid that is beneficial to human health and is biologically active as an antioxidant, freeradical scavenger, anti-inflammatory, glucose metabolism promoter, and immune system modulator.Naringenin is the main flavonoid found in grapefruit. In in vitro tests, this substance has been shown to reduce oxidative damage to DNA.Naringenin, found in grapefruit juice, has been shown to inhibit the human cytochrome P450 isoform CYP1A2, which can cause several commonly used agents to alter pharmacokinetics in the opposite way in the human (or immediate homologue) host, and even lead to the carcinogenicity of otherwise harmless substances.

Clinical applications of Bulk Naringenin Powder.

Used in the treatment of bacterial infections, sedative, anticancer drugs.Application dosage forms: suppositories, lotions, injections, tablets, capsules, etc.