Betamethasone Sodium Phosphate CAS 151-73-5 Pharma Powder Raw Materials

CAS: 151-73-5

MF:  C22H28FNa2O8P

EINECS: 205-797-0

Specification​: 99% min Betamethasone Sodium Phosphate

Sample: Betamethasone Sodium Phosphate Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Betamethasone Sodium Phosphate Powder Usage and Synthesis:

Betamethasone sodium phosphate is a glucocorticoid, glucocorticoids have anti-immune and anti-inflammatory effects and have been used clinically for many years. Betamethasone sodium phosphate is a long-acting hormonal drug, which is mostly used in clinical practice for anti-inflammatory therapy, treatment of immune diseases, anti-viral and shock treatment. It has a wide range of effects and is characterized by small dose, long half-life and significant effects compared with other glucocorticoids.

Betamethasone Sodium Phosphate is a glucocorticoid, which has anti-immune and Anti-inflammatory effects and has been used in clinical practice for many years. Betamethasone Sodium Phosphate Powder has a wide range of effects and is characterized by its low dose, long half-life and significant effects compared with other glucocorticoids.

Application/Function of Betamethasone Sodium Phosphate Powder:

Betamethasone sodium phosphate is mainly used for allergic and autoimmune diseases, and is now mostly used for active rheumatic diseases, rheumatoid arthritis, lupus erythematosus, severe bronchitis, severe dermatitis, and acute leukemia. It is also used for the comprehensive treatment of certain critical infections. Topical topical application for the treatment of allergic dermatitis, eczema, neurodermatitis, seborrheic dermatitis and pruritus, etc.Hormonal drugs with anti-inflammatory effects.

• 1、This product is used for allergic and autoimmune inflammatory diseases.
• 2、It is used for active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, acute leukemia, etc.
• 3、Used for the comprehensive treatment of certain infections.

Drug interactions

• (1) Non-steroidal anti-inflammatory and analgesic drugs may enhance their ulcerogenic effects.
• (2) It can enhance the hepatotoxicity of acetaminophen.
• (3) Combination with amphotericin B or carbonic anhydrase inhibitors may aggravate hypokalemia, and long-term combination with carbonic anhydrase inhibitors may predispose to hypocalcemia and osteoporosis.
• (4) Combined with protein anabolic hormone, it can increase the incidence of edema and make acne worse. (5) Combined with anticholinergic drugs (such as atropine) for a long period of time, may lead to increased intraocular pressure.
• (6) Tricyclic antidepressants can aggravate the psychiatric symptoms caused by them.
• (7) When combined with hypoglycemic drugs such as insulin, the dose of hypoglycemic drugs should be adjusted appropriately because it can increase blood sugar in diabetic patients.
• (8) Thyroid hormone can increase its metabolic clearance rate, so the dose of thyroid hormone or anti-thyroid drugs should be adjusted appropriately when combined with the latter.
• (9) Combined with contraceptives or estrogen preparations can enhance their therapeutic effects and adverse reactions. (10) Combined with cardiac glycosides, it may increase the occurrence of digitalis toxicity and arrhythmia.
• (11) Combination with potassium-removing diuretics may cause severe hypokalemia and weaken the sodium-removing diuretic effect of diuretics due to water and sodium retention.
• (12) Combined with ephedrine, it can enhance its metabolic clearance.
• (13) Combined with immunosuppressive agents, it may increase the risk of infection and may induce lymphoma or other lymphoproliferative disorders.
• (14) It may increase the metabolism and excretion of isoniazid in the liver and reduce the blood concentration and efficacy of isoniazid.
• (15) It can promote the metabolism of mexiletine in the body and reduce the blood concentration.
• (16) Combined with salicylate, it can reduce the concentration of plasma salicylate.
• (17) Combined with growth hormone, it can inhibit the growth-promoting effect of the latter.

Mechanism of action of Betamethasone Sodium Phosphate Powder：

Adrenocorticosteroids. They have various pharmacological effects such as anti-inflammatory, anti-allergic and immunosuppressive.

• 1、Anti-inflammatory effect: glucocorticoids reduce and prevent the tissue response to inflammation, thus reducing the manifestation of inflammation.
• 2、Immunosuppressive effects: prevent or inhibit cell-mediated immune reactions, delayed allergic reactions, and reduce the expansion of primary immune reactions.
• 3、Anti-toxic and anti-shock effects: glucocorticoids can counteract the stimulation response of bacterial endotoxin to the body, reduce cell damage and play a role in protecting the body.