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HRK tetrahydropalmatine Raw Materials Powder on sale
Product Overview:
Tetrahydropalmatine is tetrahydrobamatin, which can be prepared from tetrahydroxy coptis alkaloids. Tetrahydropalmatine can be used to prepare bamatin. Bamatin has a broad-spectrum antibacterial effect, especially against Candida albicans, and can be clinically used to treat gynecological inflammation, bacillary dysentery, enteritis, respiratory and urinary tract infections, surgical infections and conjunctivitis.
HRK tetrahydropalmatine Raw Materials Powder on sale Attributes
CAS:2934-97-6
MF:C21H25NO4
MW:355.43
EINECS:/
Specification: 99% min tetrahydropalmatine Powder
Sample:tetrahydropalmatine Powder
Packaging:1kg/bag, 25kg/drum
Brand: Raw Materials
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
HRK tetrahydropalmatine Raw Materials Powder on sale Details
tetrahydropalmatine Usage and Function.
Tetrahydropalmatine (THP) is a commonly used analgesic drug, mainly used for dull pain in the gastrointestinal and hepatobiliary systems, and pain during childbirth and dysmenorrhea. Its analgesic effect is not as good as morphine, but it is the best for chronic persistent dull pain, and the analgesic degree can reach 40% of morphine.
In addition, THP also has sedative and hypnotic effects and can be used for temporary insomnia. When using THP, the fetal ductus arteriosus needs to be monitored regularly to avoid adverse effects on the fetus.
Uses of tetrahydropalmatine.
Tetrahydropalmatine has analgesic, sedative, hypnotic and tranquilizing effects. Its analgesic effect is not as good as that of perthidine, but it is stronger than general antipyretic analgesics. DL-tetrahydropalmatine is the main active substance of the traditional Chinese medicine Corydalis yanhusuo, which can cause hypotension and bradycardia in rats by antagonizing striatal dopamine D2 receptors.
Preparation of tetrahydropalmatine.
A. Berberine hydrochloride is ring-opened in p-toluenesulfonic acid, xylene, HCl at 70°C to obtain demethylene berberine hydrochloride.
B. Demethylene berberine hydrochloride is methylated in potassium carbonate, methanol, dimethyl sulfate at 40°C to obtain palmatine hydrochloride.
C. Palmatine hydrochloride is racemized in methanol and sodium borohydride to obtain tetrahydropalmatine.
Product method of Bulk tetrahydropalmatine Powder.