Supply Alkannin Raw Materials powder Alkannin

CAS:517-88-4

MF:C16H16O5

MW:288.3

EINECS:208-245-7

Specification: 99% min Alkannin

Sample:Alkannin powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:purple

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Alkannin of Usage and Synthesis.

Modern pharmacological studies have shown that comfrey has good anti-inflammatory, anti-bacterial, anti-fertility, anti-oxidation, anti-tumor, hypoglycemic, liver protection and cardiovascular system. Anti-inflammatory and bacteriostatic effects are the traditional medicinal effects of comfrey, that is, anti-inflammatory, astringent and antipyretic effects. The anti-inflammatory components of comfrey mainly exist in alcohol extracts.

Uses of Alkannin.

It is used as antipyretic, detoxifying and anti-inflammatory drug. It can be taken internally to prevent measles, and can be used externally to promote the formation of granulation and for swelling, fire, frostbite, eczema, hydrocysts, etc. Also make a slow down agent to ease stool. In recent years, canned shikonin has also been produced by tissue culture for use as cosmetics. Levoshikonin is an enantiomer dye extracted from comfrey and comfrey, which can be used as a dye and has wound healing, anti-inflammatory, antibacterial, anti-tumor and other effects.

Pharmacological action of Alkannin.

1. Hypoglycemic effect of Comfrey leaf extract and comfrey glycan (A, B, C) have obvious hypoglycemic effect.

2. Inhibitory effect of Comfrey extract on Jingke 68-1 virus in vitro, Staphylococcus aureus, Staphylococcus albus, pseudomonas aeruginosa, Escherichia coli, typhoid bacillus, A streptococcus, B streptococcus have obvious inhibitory effect.

3. Effect on blood coagulation Intraperitoneal injection of shikonin pigments (shikonin, acetylshikonin) does not affect blood coagulation time, but can prevent the anticoagulant effect of heparin.

4. Anti-tumor effect of Comfrey extract has certain inhibitory effect on Hela cell DNA synthesis late stage (G2 stage).

5. Cancer inhibition effects Shikonin can inhibit proliferation, promote apoptosis and induce cell cycle arrest in human choriocarcinoma resistant cell lines (JAR/MTX) cultured in vitro. Experiments show that shikonin has a significantly increased inhibitory rate on the growth of choriocarcinoma resistant cells with the increase of dose and the prolongation of action time.

Product method of Bulk Alkannin Powder.

It exists in the roots of comfrey, Xinjiang comfrey and other plants. Shikonin can also be produced by cell culture of comfrey.