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Supply Berberine Hydrochloride Raw Materials powder Berberine Hydrochloride
Product Overview:
Berberine hydrochloride, also known as berberine hydrochloride, has been used in clinical practice for a long time as a heat-clearing detoxification and antibacterial drug. It is often used in the treatment of dysentery, acute gastroenteritis, chronic cholecystitis, conjunctivitis, suppurative otitis media and other diseases, and has significant curative effect. Berberine hydrochloride is an isoquinoline alkaloid, which exists in many plants of 4 families and 10 genera, such as Berberine family. Yellow acicular crystals of berberine can be precipitated from ether. Berberine is a quaternary ammonium alkaloid, and its salts have a relatively small solubility in water, such as 1∶500 for hydrochloride and 1∶30 for sulfate.
Supply Berberine Hydrochloride Raw Materials powder Berberine Hydrochloride Attributes
CAS:633-65-8
MW:371.81
EINECS:211-195-9
Specification: 99% min Berberine Hydrochloride
Sample:Berberine Hydrochloride powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance:yellow
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Supply Berberine Hydrochloride Raw Materials powder Berberine Hydrochloride Details
Berberine Hydrochloride of Usage and Synthesis.
Berberine hydrochloride can inhibit dysentery bacillus, Escherichia coli, Diplococcus pneumoniae, Staphylococcus aureus, Streptococcus, typhoid bacillus and amoeba. It is mainly used for intestinal infection and dysentery. It was also found to have antiarrhythmic effect. Berberine has strong antitumor activity in vivo and in vitro and can induce B16 cell differentiation. It has synergistic effect with cytarabine hydrochloride in vitro.
Berberine has antibacterial effect on hemolytic streptococcus, Staphylococcus aureus, gonorrhoeae, Fredricki and Shigella dysenteriae, and can enhance white blood cell phagocytosis. Berberine hydrochloride (commonly known as berberine hydrochloride) has been widely used in the treatment of gastroenteritis, bacillary dysentery, tuberculosis, scarlet fever, acute tonsillitis and respiratory infection also has a certain effect.
Uses of Berberine Hydrochloride.
It has a weak inhibitory effect on bacteria (mainly dysentery, Escherichia coli, staphylococcus aureus), and reduces the number of pili on the surface of the bacterial body, so that the bacteria is not easy to attach to the human cells, and can reduce the gastrointestinal ulcer of the stomach and duodenum.
It is effective in treating intestinal infections such as gastroenteritis, bacillary dysentery, eye conjunctivitis and suppurative otitis media. Recently, it has also been found to block alpha-receptor, anti-arrhythmia effect.
Usage: It is mainly used as a raw material for intestinal infections such as gastroenteritis and bacillary dysentery caused by sensitive pathogens.
Pharmacological action of Berberine Hydrochloride.
The antibacterial spectrum is wide, and it has antibacterial effect on many kinds of gram-positive and gram-negative bacteria in vitro, including hemolytic streptococcus, Staphylococcus aureus and Vibrio cholerae. Meningococcus, Shigella dysentery, typhoid bacillus, diphtheria bacillus have strong inhibitory effect, low concentration of bacteriostasis, high concentration of bactericidal. It also has certain inhibitory effect on influenza virus, amoeba, leptospira and some skin fungi. In vitro experiments show that berberine can enhance the phagocytosis of leukocyte and hepatic reticuloendothelial system. Dysentery bacillus, hemolytic streptococcus, staphylococcus aureus and so on are easy to develop resistance to this product. There is no cross-resistance between this product and penicillin, streptomycin, etc.
Product method of Bulk Berberine Hydrochloride Powder.
Extracted with sulfuric acid after pulverized with ten virtues or three needles, precipitated with hydrochloric acid, and then refined.