Raw Materials Gymnema Sylvestre Extract powder

CAS:90045-47-9

MF:/

MW:/

EINECS:283-415-1

Specification​: 99% min Gymnema Sylvestre Extract Powder

Sample:Gymnema Sylvestre Extract Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Brown

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Gymnema Sylvestre Extract Powder Usage and Synthesis.

Gymnemasylvestree Extract is extracted from the dried stems and leaves of Gymnemasylvestree, a plant of the family Romeraceae. Gymnema sylvestre is also known as Wu Zhi Vine or Goat's Horn Vine, which is distributed in India, Vietnam, Indonesia, Australia, Tropical Africa, and Guangdong, Guangxi, Yunnan, Fujian, Zhejiang and Taiwan in China. Its extract is mainly composed of total triterpenoid saponins, flavonoid glycosides, anthocyanins, polysaccharides and other components.

Total saponin is the active ingredient, which consists of a variety of saponin-like compounds, of which the most abundant is the spoon vine acid.

Spoonful of vine extract has the effect of dispelling wind and cooling blood, reducing swelling and relieving pain, stomachic and diuretic, and is used for wind-cold and damp paralysis, diabetes, vasculitis and so on.

In recent years, scholars at home and abroad have found that it has the effects of lowering blood sugar, lowering blood lipids, anti-atherosclerosis, suppressing sweetness, anti-caries and suppressing obesity, etc., and it has broad application prospects in the field of drugs, functional foods and health care products.

Uses of Gymnema Sylvestre Extract.

Spoonful of Vine Extract is extracted from the dried stems and leaves of Spoonful of Vine, a plant of the family Lauraceae, and has a variety of efficacies and effects.

Firstly, spoonbill vine extract can clear heat and detoxify, dispel wind and relieve pain, and is used for rheumatism and arthralgia, carbuncle boils and poison, poisonous snake bites and other diseases, which has certain medicinal value.

Secondly, Spoonbill vine extract can promote hepatic glycogen synthesis, inhibit hepatic glycogen decomposition, reduce hepatic glycogen, promote glycolysis, and at the same time, it can increase the utilisation of glucose by peripheral tissues and organs, thus inhibiting the secretion of glycemic hormone by adrenaline and glucagon, inhibiting the absorption and digestion of carbohydrates in the small intestine, and regulating the activity of enzymes related to glucose metabolism, so that it can achieve the effect of weight loss.

In addition, the spoon vine extract also has the effect of hypoglycaemic and inhibit the sweet reaction, can inhibit the desire to eat sweets, inhibit the body's absorption of sugar, lowering blood sugar, help repair the damaged cells of the pancreas, improve insulin secretion, diabetic patients with a certain degree of adjuvant therapy.

It should be noted that pregnant women should be cautious to use spoon vine extracts

Pharmacological effect of Gymnema Sylvestre Extract.

1. Hypoglycaemic effect

The extract of Vitis vinifera has a mildly elevating effect on normal blood glucose, but when combined with glucose or sucrose, it can significantly inhibit the rise in blood glucose levels and significantly reduce the secretion of plasma insulin.

2.Antihyperlipidemic and anti-atherosclerotic effects

Vitis vinifera leaf extract can reduce serum triglyceride, total cholesterol, very low density lipoprotein (LDL) cholesterol and low density lipoprotein (LDL) cholesterol levels in hyperlipidaemic rats, and rebound the low high-density lipoprotein (HDL) cholesterol and anti-atherosclerotic index in hyperlipidaemic rats.

3.Weight loss

The weight loss effect of Garcinia Cambogia (GA) is due to the fact that in addition to reducing the desire for sweets, GA can also reduce the body's absorption of sugar.

GA can reduce the desire for sweets by reducing the sweetness of food, but not making it completely devoid of sweetness, so that the effect can be maintained for 1-2 h. Inhibiting the absorption of sugar is through the control of the intestinal absorption of sugar molecules in the digestive process, which can effectively reduce the metabolism of sugar, so as to change the absorption of sugar, so as to achieve the effect of altering the level of blood glucose.

4. Anti-tumour and anti-inflammatory effects

The primary characteristics of tumours are malignant proliferation, imbalance between cell proliferation and apoptosis, anti-proliferation and pro-apoptosis are effective strategies for the treatment of tumours. In vitro, gymnemagenol in Gymnema sylvestre can inhibit HepG2 cells (human hepatocellular carcinoma cells), and Gymnema sylvestre extract has significant activity against breast cancer and lung cancer epithelial cells.

Ingredient extraction of Gymnema Sylvestre Extract.

Crushed the dried leaves of the plant of Vitis vinifera → Soxhlet extraction with ether as solvent to remove crude fat → extraction at 70℃, ethanol concentration of 50%, and material-liquid ratio of 1:15 (m/v) for 2h → filtration → concentration by vacuum rotary evaporation → obtaining aqueous solution of Vitis vinifera acid → purified Vitis vinifera acid by passing through the macroporous adsorbent resin.