Methimazole CAS 60-56-0 Raw Materials

CAS: 60-56-0

MF: C4H6N2S

Specification​: 99% min Methimazole Powder

Sample:  Methimazole Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Methimazole Powder Usage and Synthesis:

Methimazole is a medication used to treat hyperthyroidism, a condition in which the thyroid gland produces too much thyroid hormone. It works by inhibiting the production of thyroid hormones in the thyroid gland. Methimazole is available in tablet form and is typically taken once or twice a day. It may take several weeks to see the full effects of the medication.
Common side effects of methimazole include nausea, vomiting, headache, and rash. In rare cases, it can cause serious side effects such as liver damage or a decrease in white blood cell count. Methimazole should be used with caution in pregnant women as it can cross the placenta and affect the developing fetus.

Pharmacokinetics of Methimazole Powder:

Methimazole is an antithyroid drug that inhibits peroxidase in the thyroid gland and prevents the oxidation of iodide absorbed into the thyroid gland. It is indicated for various types of hyperthyroidism and diffuse enlargement of the thyroid gland. It is very effective in patients with milder thyroid, mild, and moderate enlargement, and the course of treatment is usually 12-18 months.

Methimazole is an imidazole antithyroid drug, not a hormonal drug, marketed under the common names of tabazol, methimazole, and methiothiazole, mainly used for the treatment of hyperthyroidism, by inhibiting the peroxidase system, impeding the synthesis of thyroxine (T4) and triiodothyronine (T3),

which has been observed in animal experiments to inhibit the synthesis of antibodies by B lymphocytes and reduce the circulating thyroid-stimulating In animal studies, it has been observed that it can inhibit antibody synthesis by B lymphocytes, reduce the level of thyroid-stimulating antibodies in blood circulation, and normalize the function of suppressive T cells.

Clinical Application of Methimazole Powder:

Methimazole is an antithyroid drug that reduces the synthesis of thyroxine by inhibiting enzymes in the thyroid gland. Methimazole is mainly used in patients with hyperthyroidism, in patients with goiter, in pre-surgical treatment of the thyroid gland and in intermittent treatment after radioactive iodine. When patients use methimazole, they need to follow the advice of their doctor. If patients use too much, it may lead to underactive thyroid gland.

In addition, thyroid function should be monitored during use to assess the efficacy of the drug and to prevent adverse effects associated with underactive thyroid. Prepared by reaction of aminoacetaldehyde diethyl acetal with methyl isothiocyanate. It can also be made from the reaction of thiocyanic acid with N-substituted aminoacetal. Also prepared from the reaction of thiocyanic acid with N-substituted aminoacetal.
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