Raw material Codonopsis Root Extract powder

CAS:141726-23-0

MF:C16H18O2

MW:242.31

EINECS:/

Specification: 99% min Codonopsis Root Extract powder

Sample:Codonopsis Root Extract powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Brown

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Codonopsis Root Extract powder Usage and Synthesis.

Dangshen is a common Chinese herb with many benefits. Dangshen powder is a powder made by grinding Dangshen into a powder that is easy to take. Codonopsis powder can be used to treat symptoms such as neurasthenia, anaemia, atrophic disease, leukaemia and thrombocytopenia.

Dangshen powder can also improve human immunity, promote blood circulation and enhance physical fitness. In animal experiments, Radix ginseng powder can increase the number of red blood cells and decrease the number of white blood cells, and the effectiveness of oral administration is more significant than that of subcutaneous injection.

Therefore, Codonopsis pilosula powder can be used as an effective traditional Chinese medicine treatment and health care product.

Uses of Codonopsis Root Extract powder.

BLOOD REPLENISHMENT: Codonopsis powder can increase the content of red blood cells and haemoglobin, which helps to replenish blood. Used in combination with herbs such as Angelica sinensis and Radix Rehmanniae, Radix et Rhizoma Ginseng Powder is effective for conditions such as anaemia, atrophic diseases, leukaemia and thrombocytopenia.

Enhancement of immunity: Codonopsis pilosula powder can improve the immunity of the body and enhance the resistance. Ginseng powder is also effective in neurasthenia, restless sleep, easy to wake up and other symptoms.

Promote erythropoiesis: Radix ginseng powder can promote erythropoiesis in the spleen, which helps to increase the number of red blood cells. Rabbits subcutaneously injected with aqueous and alcoholic extracts of Radix et Rhizoma Ginseng or fed Radix et Rhizoma Ginseng powder can increase the number of erythrocytes and decrease the number of leukocytes.

Pharmacological Effect of Codonopsis Root Extract powder.

1. Immunomodulatory effect: Codonopsis pilosula can enhance phagocytosis of reticuloendothelial system, can significantly increase the number of macrophages and enhance phagocytosis.

It has significant enhancement effect on non-specific immune function, cellular immune function, humoral immune function and interleukin. It can also enhance the immune function in the inhibited state. It also has anti-metamorphic effect.

2. Enhancement of metabolism: Codonopsis pilosula has significant enhancement on intracellular DNA, RNA, ACPase, ATPase, sugar, acid esterase and succinate dehydrogenase activity.

3. Actions on endocrine and elevation of blood glucose: Radix Codonopsis pilosulae can increase plasma corticosterone content in mice, and its action site is in pituitary gland and hypothalamus. Its decoction can raise blood sugar. After removing polysaccharide, it loses the effect of elevating blood sugar.4. Cardiotonic effect: Codonopsis pilosula has cardiotonic effect, which can make its left ventricular early diastolic filling time shorten significantly in patients with coronary artery disease, and the cardiac output of left ventricular systolic function increase significantly, and it can reduce the myocardial oxygen consumption, and improve the blood supply of the myocardium.5. Haematopoietic effect: rabbits orally consume Codonopsis pilosula powder, it can make the number of red blood cells and haemoglobin increase significantly; however, it can make the number of leukocytes After removing polysaccharide, it loses the effect of elevating blood sugar.

4. Cardiotonic effect: Radix Panax ginseng has cardiotonic effect, which can shorten the left ventricular early diastolic filling time of patients with coronary artery disease, increase the cardiac output of left ventricular systolic function, reduce myocardial oxygen consumption and improve the blood supply of myocardium.

5. Blood-generating effect: rabbits orally consumed Codonopsis powder can make the number of red blood cells and haemoglobin increase significantly; however, it can make the number of white blood cells decrease, and this effect is related to the spleen.

6. Effects on central nervous system: Decoction of Radix Codonopsis pilosulae has inhibitory effect on spontaneous activity of mice. It can improve the memory disorder of mice, enhance the memory process, and improve the memory ability of both left and right hemispheres at the same time.

7. Antihypertensive effect: Intravenous or intraperitoneal injection of aqueous extract of Radix et Rhizoma Ginseng with alcoholic extract can reduce the blood pressure of anaesthetised dogs. According to preliminary analyses, it is considered to be of terminal nature and has certain anti-adrenergic-like effects.

Extraction method of Bulk Codonopsis Root Extract powder.

Hydroalcoholic

The extraction process of polysaccharide by aqueous-alcoholic precipitation is as follows: weighing the appropriate amount of slices of Codonopsis pilosula → reflux of petroleum ether → reflux of ethanol → adding a certain amount of water, reflux extraction for a certain period of time → centrifugation → filtrate concentration under reduced pressure → addition of ethanol precipitation of polysaccharides → refrigerator static → centrifugation → alcoholic precipitates were washed with anhydrous ethanol, acetone, and ether once each → vacuum drying at 40 ℃ to a constant weight → polysaccharide samples.