Benzhexol Hydrochloride CAS 52-49-3 Raw Powder Materials

CAS: 52-49-3

MF:  C20H31NO.ClH

EINECS: 200-142-5

Specification​: 99% min Benzhexol Hydrochloride

Sample: Benzhexol Hydrochloride Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Benzhexol Hydrochloride Powder Usage and Synthesis:

Benxoxol hydrochloride is a commonly used drug, it is a powerful analgesic and cough suppressant. Its chemical name is (1R,2R)-2-[(4S)-4-phenyl-4-(2-pyridyl)-1-piperazinyl]-1-cyclohexanol hydrochloride. Benzoxol hydrochloride is a white crystalline powder which can be prepared by chemical synthesis.

The pharmacological action of benxoxol hydrochloride is mainly to relieve pain and cough by inhibiting the central nervous system. It can reduce pain and the sensation of coughing by binding to specific receptors in the brain. Benzoxol hydrochloride also reduces muscle cramps and inflammation.

Benxoxol hydrochloride is a central anti-cholinergic anti-Parkinson's drug, which selectively blocks the cholinergic neural pathway in the striatum, but has little peripheral effect, which is beneficial to restore the balance of dopamine and acetylcholine in the brain of patients with Parkinson's disease, and improve the symptoms of Parkinson's disease. For Parkinson's disease, Parkinson's syndrome. It can also be used for extrapyramidal disorders caused by drugs. Its pharmacological action and side effects are similar to belladonna alkaloids in nature.

Application/Function of Benzhexol Hydrochloride Powder:

The main applications of benxoxol hydrochloride are analgesia and cough relief. It can be used to relieve various types of pain, including headache, toothache, joint pain, muscle pain and neuralgia. In addition, benzoxol hydrochloride can be used to treat coughs, especially those caused by colds, flu and bronchitis.

The dosage and use of benxoxol hydrochloride should be determined according to the specific situation of the patient. In general, the oral dose for adults is 10-20 mg per session, and the maximum daily dose should not exceed 80 mg. The dosage for children should be based on weight and age. Benxoxol hydrochloride can be administered orally or by injection, but should not be used long-term.

This product is a central anti-cholinergic anti-Parkinson's drug, which selectively blocks the cholinergic neural pathway in the striatum, but has little peripheral effect, so as to help restore the balance of dopamine and acetylcholine in the brain of patients with Parkinson's disease, and improve the symptoms of Parkinson's disease

Mechanism of action of Benzhexol Hydrochloride Powder: Mechanism of Action of Benzhexol hydrochloride powder:

Benxol hydrochloride is a commonly used drug, but it does have some side effects and caveats. Benxoxol hydrochloride may cause dizziness, nausea, vomiting, constipation, dry mouth and other adverse reactions. In some cases, benzoxol hydrochloride can also cause serious side effects such as allergic reactions, arrhythmia and respiratory depression. Therefore, the use of benxoxol hydrochloride should follow your doctor's advice and should not exceed the recommended dosage and duration of use.

In summary, benxoxol hydrochloride is a commonly used drug that can be used to relieve various types of pain and cough. However, the dosage and time should be paid attention to when using benxol hydrochloride to avoid the occurrence of adverse reactions and side effects. If you experience any discomfort or questions, consult your doctor.

Preparation process of Benzhexol Hydrochloride Powder:

Benxoxol hydrochloride has a central M receptor blocking effect, which can counteract the excitatory function of acetylcholinergic system in the striatum nigra of central nervous system. The blocking effect on peripheral M receptor is weak, the blocking effect on vagus nerve is atropine I/Io, the dilating effect on pupil is its I / 3, and the spasmolytic effect is its 112, so the inhibitory effect on glands and smooth muscle is weak. Acetylcholine is an excitatory neurotransmitter in the extrapyramidal substantia nigrostriatum pathway. Palsy tremor is a degenerative disease in the substantia nigra striatum pathway, resulting in decreased inhibition of dopamine and increased excitatory effect of acetylcholine, resulting in clinical symptoms. Therefore, benzoxol can be effective in the treatment of paralysis tremor through central anticholinergic action.