vitamin b3 raw Materials powder Nicotinamide

CAS:98-92-0

MF:C6H6N2O

MW:122.12

EINECS:202-713-4

Specification: 99% min vitamin b3 powder

Sample:vitamin b3 powder

Packaging:1kg/bag, 25kg/drum

Brand:Henrikang

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

vitamin b3 powder Usage and Synthesis.

Niacinamide and nicotinic acid are common in most sound combinations, and nicotinic acid also produces nicotinamide in animals. Pellagra occurs when the body is deficient in niacin and niacinamide. So they prevent pellagra. They play a role in the metabolism of proteins and sugars, improving nutrition in humans and animals. In addition to medicine, it is also widely used as a food and feed additive. Worldwide production capacity has exceeded 30,000 tons. In Japan, niacinamide is used in medicine for 40% and feed additives for 50%. Food additives account for 10%. Niacin and niacinamide are non-toxic and naturally contained in animal liver, kidney, yeast and rice sugar. The LD50 of niacinamide to rat subcutaneous injection is 1.7 g/kg.

Uses of vitamin b3.

1. Moisturize, control oil and reduce blackheads

Niacinamide can effectively reduce transdermal water loss, although the effect of single use is not as good as hyaluronic acid and glycerin, but the effect of combined use is definitely 1+1>2; Niacinamide can calm down the sebaceous glands in the "excited" state, thus achieving oil control and reducing the effect of blackheads and acne.

2. Good wrinkle resistance

The anti-wrinkle ability of niacinamide lies in its ability to activate ATP, provide keratin cell vitality, increase collagen synthesis, and has a good synergy, and can be used with other anti-wrinkle ingredients.

3. Good auxiliary sunscreen effect

The damage caused by ultraviolet light to the human body is not only tanning, but also leads to the occurrence of immune suppression, and even skin cancer. Many studies at home and abroad have shown that niacinamide can effectively reduce the occurrence of skin photoimmunosuppression under ultraviolet irradiation.

4. Good gentleness

Compared with vitamin C, phloroglucinol derivatives and other ingredients, The mild nature of niacinamide is not bad, many people's skin can basically be used, but it is still necessary to pay attention to the problem of skin tolerance, such as The Ordinary whitening essence of 10% niacinamide concentration, or has a certain irritation. Therefore, it is best to pass the skin tolerance test before use to determine the tolerance before use, and be careful not to use with acid-containing products, such as salicylic acid and fruit acid to prevent excessive irritation to the skin.

Whitening principle of vitamin b3.

First, niacinamide can interfere with the transport of melanin, restrict melanin in melanocytes, prevent melanocytes from continuing to produce melanin, and avoid the transmission of melanin to the skin surface to make the skin black, so as to achieve the effect of whitening.

Second, niacinamide has been proven to have a good anti-glycation effect, and the substance produced by skin glycation is brown, which will make the skin look black, and the anti-glycation of niacinamide helps to whiten the skin, thereby brightening the skin tone.

Product Methods of vitamin b3.

Put niacin, boric acid and ammonia into the reaction pot, stir through the ammonia gas, heat up to dissolve; Then distillation to recover ammonia, 120~C after the transfer into the dewatering pot to continue concentrating; When the temperature reaches 145℃, liquid ammonia is added, and the ammonia reaction continues at 185 ~ 190℃ for 20 ~ 30h. Then the temperature was lowered to 130℃, diluted with distilled water, activated carbon was added, and decolorized by ammonia for 2h at 70~80~C; After the reaction, the filtrate was filtered while hot. The filtrate was cooled out in water for 24h, separated and crystallized, washed and dried with ethanol to obtain the finished product with a yield of 89%.