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Lisinopril raw Materials powder Lisinopril
Product Overview:
Lisinopril is a third-generation angiotensin-converting enzyme inhibitor, a lysine derivative of enalapril, which was marketed in the United States in 1987 for the treatment of hypertension and is a first-line treatment drug for antihypertensive diseases. Pharmacological characteristics and Enalapril (Enalapril) similar, has a strong angiotensin-converting enzyme inhibition, rapid effect, long action time, take medicine once a day. The inhibition of ACE was 6 to 8 times that of captopril and 1 to 3 times that of Benazepril. It can significantly reduce total peripheral resistance and blood pressure, but it is not accompanied by reflex tachycardia.
Lisinopril raw Materials powder Lisinopril Attributes
CAS:76547-98-3
MF:C21H31N3O5
MW:405.49
EINECS:278-488-1
Specification: 99% min Lisinopril powder
Sample:Lisinopril powder
Packaging:1kg/bag, 25kg/drum
Brand:Henrikang
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Lisinopril raw Materials powder Lisinopril Details
Lisinopril powder Usage and Synthesis.
Lisinopril can reduce lung wedge pressure, increase stroke volume, increase left ventricular ejection fraction and improve cardiac function in patients with heart failure. It can increase renal blood flow, reduce renal vascular resistance and increase glomerular filtration rate. Use alone or in combination with other drugs to treat various degrees of hypertension and renal hypertension that have failed to be treated with other antihypertensive drugs, can also be used alone or in combination with digitalis and diuretics to treat congestive heart failure. It can also be used as adjuvant therapy for hemodynamic stable patients after acute myocardial infarction.
Uses of Lisinopril.
The efficacy of lisinopril alone was slightly better than atenolol or hydrochlorothiazide in the treatment of mild and moderate hypertension. In the treatment of severe hypertension, the efficacy is the same as metoprolol or nifedipine; The treatment of congestive heart failure is superior to captopril, and can increase left ventricular ejection fraction, enhance mobility and improve quality of life. At present, this product is a second-line drug for the treatment of hypertension and congestive heart failure.
Pharmacological action of Lisinopril.
This product is a lysine derivative of enalaprilat and has a strong angiotensin-converting enzyme inhibitory effect. Its characteristic is that it can produce pharmacological effects in vivo without liver transformation, and the effect appears late, but the effect is maintained for a long and stable time.
Product Methods of Lisinopril.
