Chlorpromazine hydrochloride Raw Materials powder Chlorpromazine hcl

CAS:69-09-0

MF:C17H20Cl2N2S

MW:355.33

EINECS:200-701-3

Specification​: 99% min Chlorpromazine hydrochloride powder

Sample:Chlorpromazine hydrochloride powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Chlorpromazine hydrochloride Powder Usage and Synthesis.

Chlorpromazine hydrochloride is a representative drug of phenothiazines, which is a blocking agent of central dopamine receptors and has many pharmacological activities.

1, treatment of psychosis: used to control schizophrenia or other mental disorders of excitement, agitation, nervousness, hallucinations, delusions and other symptoms, depression symptoms and stupor symptoms of poor efficacy.

2, vomiting: almost all kinds of causes of vomiting, such as uremia, gastroenteritis, cancer, pregnancy and drug-induced vomiting are effective, can also be used to treat intractable hiccup, but motion sickness vomiting is ineffective.

3, low temperature anesthesia and artificial hibernation: used for low temperature anesthesia can prevent shock.

4. Combined with analgesics to treat severe pain in patients with advanced cancer.

5. Treat heart failure.

6. Used in the treatment of gigantism.

Use of Chlorpromazine hydrochloride.

1. Treatment of psychosis: It is used to control the symptoms of excitement, agitation, nervousness, hallucinations, delusions and other symptoms of schizophrenia or other psychosis, and the efficacy of depression symptoms and stupor symptoms is poor.

2. Anti-vomiting: It is effective for vomiting caused by almost all kinds of reasons, such as uremia, gastroenteritis, cancer, pregnancy and drug-induced vomiting. It can also be used to treat intractable hiccup, but it has no effect on motion sickness vomiting.

3. Low temperature anesthesia and artificial hibernation: It can prevent shock during low temperature anesthesia.

4. Used in combination with analgesics to treat severe pain in patients with advanced cancer.

5. Treat heart failure.

6. Used to treat gigantism.

Substituting benzidine, o-dianisidine and o-toluidine in the microdetermination of hemoglobin and peroxidase.

Pharmacological Effect of Chlorpromazine hydrochloride.

Product Method of Bulk Chlorpromazine hydrochloride Powder.

It is obtained by condensation and salt formation of 2-chlorophenthiazine [92-39-7]. 1. Condensation add 2-chlorophenthiazine and toluene into the reaction pot, then add sodium hydroxide, stir and heat reflux, remove water, drop toluene solution of 1-chloro-3-dimethylamine-propane at 110℃, reduce pressure and recover toluene to obtain chlorpromazine, C17H19CIN2S, [50-53-1]. 2. To salt, stir chlorpromazine and isopropyl alcohol and heat to 40℃, and pass dry hydrogen chloride to pH4-5 to obtain chlorpromazine hydrochloride into salt.