Lansoprazole Raw Material Lansoprazole Powder

CAS: 103577-45-3

MF: C16H14F3N3O2S

MW:369.36

EINECS: 2017-001-1

Specification​: 99% min Lansoprazole 

Sample: Lansoprazole Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Lansoprazole Raw Materials Usage and Synthesis

China Lansoprazole Raw Material Lansoprazole Powder Factory Supply Lansoprazole Raw Material, High Quality Lansoprazole Powder Purity 99% Lansoprazole Raw Powder CAS 103577-45-3 Lansoprazole Raw Powder.

Lansoprazole Raw Material is used in the treatment of duodenal ulcers, etc. Lansoprazole Raw Powder has a significant inhibitory effect on basal gastric acid and gastric acid secretion due to all stimulants.

Uses and functions of Lansoprazole Powder

Lansoprazole Powder can be rapidly converted to hyposulfonic acid and hyposulfonyl derivatives through the wall cell membrane under acidic condition to exert its efficacy, and it has an inhibitory effect on Helicobacter pylori (Hp), which is 4 times higher than that of omeprazole.

Lansoprazole Raw Powder is clinically used in the treatment of duodenal ulcer, gastric ulcer, anastomotic ulcer, reflux oesophagitis, and Zollinger-Ellison syndrome (Zollinger-Ellison syndrome; gastrinoma), with remarkable efficacy.

Pharmacological Effects of Lansoprazole Raw Powder

Lansoprazole, a substituted benzimidazole derivative, is a second proton pump inhibitor. It is converted to an active sulfenamide derivative in the acidic environment of the fine tubules of the cells of the gastric wall, which is attached to the sulfhydryl group of H+-K+-(ATP) adenosine triphosphatase (the final step in the process of gastric acid secretion catalysed by the enzyme) and so blunts the enzyme and inhibits gastric acid secretion, which is regulated by both the central and the peripheral.

Production method of Raw Lansoprazole Powder

To 2,3-dimethylpyridine was added glacial acetic acid and a portion of 30 per cent hydrogen peroxide, which was heated and the remaining hydrogen peroxide was added. At the end of the reaction, the solvent was evaporated under reduced pressure to give compound (I). It was slowly added to the mixed acid and heated to give the nitration product (II).

A solution of trifluoroethanol was reacted under alkaline conditions for several hours, the nitration product (II) was added dropwise and heated to give the substitution product (III).