Orlistat Raw Material Orlistat Powder Loss Weight Orlistat

CAS: 96829-58-2

MF: C29H53NO5

MW:495.73

EINECS: 639-755-1

Specification​: 99% min Orlistat 

Sample: Orlistat Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Orlistat Raw Materials Usage and Synthesis

China Orlistat Raw Material Orlistat Powder Factory Supply Orlistat Raw Material, High Quality Orlistat Powder Purity 99% Orlistat Raw Powder CAS 96829-58-2 Orlistat Powder is now internationally recognised as a new weight loss and lipid lowering drug. Orlistat Raw Powder is a long-acting, potent and specific gastrointestinal lipase inhibitor.

Manufactory Supply Orlistat Raw Material, Orlistat Powder and Pharmaceutical intermediates Loss Weight Orlistat High Quality Orlistat Purity 99% Orlistat Raw Powder CAS 96829-58-2.

Uses and functions of Orlistat Powder

This product in combination with a mild low-calorie diet is indicated for the long-term treatment of obese and overweight individuals, including those who have developed risk factors associated with obesity.

This product has long-term efficacy for weight control (weight loss, weight maintenance and prevention of rebound).

Taking orlistat reduces the risk factors associated with obesity and the incidence of other diseases associated with obesity, including hypercholesterolaemia, type II diabetes mellitus, impaired glucose tolerance, hyperinsulinaemia, hypertension, and reduces the amount of fat in the organs.

Pharmacological Effects of Orlistat Raw Powder

Orlistat is a long-acting and potent specific gastrointestinal lipase inhibitor, white or off-white powder at room temperature, insoluble in water, soluble in chloroform, soluble in ethanol, inactivates the enzyme through the formation of covalent bonds with the active serine sites of gastric lipase and pancreatic lipase in the lumen of the stomach and small intestine.

Fat in food cannot be broken down into free fatty acids and monoacylglycerol, thus fat cannot be absorbed and utilised, thus reducing calorie intake in the body and controlling body weight.

Orlistat belongs to the lipase inhibitor class of weight loss drugs, which is a hydrated derivative of lipostatin (lipoinhibitor), which reduces the absorption of dietary fat, thus leading to weight loss.

It has a potent and selective inhibition of gastric lipase and pancreatic lipase, and has no effect on other digestive enzymes (amylase, trypsin, chymotrypsin) and phospholipase, etc. It does not affect the absorption of carbohydrates, proteins and phospholipids. The drug is not absorbed by the gastrointestinal tract, the inhibition of lipase is reversible.

Production method of Raw Orlistat Powder

Raw Orlistat Powder is White crystalline powder, almost insoluble in water, soluble in chloroform, very soluble in methanol and ethanol, easily pyrolysed, melting point is 40℃～42℃. Its molecule is a diastereoisomer containing four chiral centres, at a wavelength of 529nm, its ethanol solution has a negative spin.