Bromhexine Hydrochloride CAS 611-75-6 Raw Materials Powder

CAS: 611-75-6

MF: C14H21Br2ClN2

MW: 412.59

EINECS: 210-280-8

Specification​: 99% min Bromhexine Hydrochloride

Sample: Bromhexine Hydrochloride Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Bromhexine Hydrochloride Powder Usage and Synthesis.

Bromhexine Hydrochloride is a mucous dissolved agent to directly act on the bronchial glands to promote the release of the lysosome of mucous secretory cells, to differentiate and split mucosaccharide fibers in sputum, and to dilute sputum for easy cough up. Clinically 

Bromhexine HCL is mainly used for acute and chronic bronchitis, asthma, bronchiectasis and emphysema, especially for patients with difficulty in coughing up white mucous sputum and for critical emergencies caused by extensive sputum obstruction of small bronchi. 

Bromhexine HCL Powder preparations are available in oral tablets, solution, aerosol, injection, lyophilized powder injection, infusion and other dosage forms.

Application/Function of Bromhexine Hydrochloride Powder.

Bromhexine Hydrochloride Powder is a novel mucous soluble expectorant to be synthesized by the system of bromhexine hydrochloride powder according to the structure of the active ingredient (muscozine hydrochloride) in the medicinal plant anthracis; it is suitable to dissolve mucous phlegm strongly. It can make mucosaccharide fiber differentiation and cracking in sputum, also can inhibit the synthesis of mucosaccharide, reduce the content of sialic acid (one of the components of acid mucosaccharide) in sputum, thus reducing the viscosity of sputum. After oral administration, there is an unpleasant expectorant effect, so that sputum is easy to cough up, so that the respiratory tract is smooth.

Bromhexine Hydrochloride Powder is used clinically for the treatment of acute and chronic bronchitis, asthma, bronchiectasis, and emphysema, especially for patients with difficulty in coughing up white mucous sputum, and for shortness of breath caused by extensive obstruction of small bronchus by sputum. 

Adverse reactions: Occasional nausea and stomach discomfort after taking this product, which can disappear after reduction or withdrawal. A few patients had temporary elevation of serum transaminase. It should be used with caution in patients with gastric ulcer. This product has very little toxicity.

Bromhexine HCL is a new mucolytic expectorant, which can differentiate and lysate mucosaccharide fibers in sputum, reduce the viscosity of sputum and increase the secretion of sputum, so as to dilute sputum and make it easy to cough up, smooth the airway and relieve symptoms.

Character of Bromhexine HCL Powder

• Bromohexane hydrochloride new film: white film.
• Bromohexine hydrochloride for injection: white or white - like loose mass or powder.
• Bromohexine hydrochloride injection: colorless clear liquid.
• Bromohexine hydrochloride glucose injection: colorless clear liquid.

Pharmacological effect of Bromhexine HCL Powder

This product is a semi-synthetic product obtained from aracanthine, which has the effect of reducing and breaking mucosaccharide fibers in sputum, reducing the viscosity of sputum, thinning sputum and making it easy to cough up.

Secondly, it can inhibit the synthesis of acid glycoprotein in mucus glands and goblet cells, reduce the content of sialic acid (one of the components of acid mucosaccharide) in sputum, and reduce the viscosity of sputum, which is conducive to sputum cough up. 

The expectorant effect of this drug is related to its promotion of ciliary movement of respiratory mucosa and its malignant expectorant effect. The patient's ventilation improved as sputum was coughed up.