Ceftriaxone Sodium Raw Material Powder

CAS: 74578-69-1

MF: C18H19N8NaO7S3

MW: 578.57

EINECS: 277-930-0

Specification​: 99% min Ceftriaxone Sodium

Sample: Ceftriaxone Sodium Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Ceftriaxone Sodium Powder Usage and Synthesis.

Ceftriaxone Sodium Powder is a water-soluble β-lactam cephalosporin, Ceftriaxone Sodium CAS 74578-69-1 is a non-gastrointestinal, semi-synthetic. Ceftriaxone Sodium is a non-gastrointestinal, semi-synthetic, broad-spectrum, long-acting third-generation cephalosporin antibiotic.

Ceftriaxone Sodium Raw Materials Good therapeutic results have been achieved in the treatment of lower respiratory tract infections, skin tissue. Good therapeutic results have been achieved in the treatment of lower respiratory tract infections, skin tissue, urinary tract infections, bone and joint infections and bacterial septicemia conditions.

Ceftriaxone Sodium Powder is a third-generation cephalosporin antibiotic. It has powerful activity against Enterobacteriaceae bacteria. It is used for the treatment of respiratory tract infections, urinary tract infections, gonorrhea and preoperative infection prevention.

Application/Function of Ceftriaxone Sodium Powder.

Ceftriaxone Sodium Powder is a water-soluble β-lactam cephalosporin, a non-gastrointestinal, semi-synthetic, broad-spectrum, long-acting third-generation cephalosporin antibiotic, very sensitive to most Gram-positive and negative bacteria, with a broad antibacterial spectrum, strong antibacterial action, resistance to enzymatic degradation, low toxicity, strong tissue penetration, and long half-life.

The β-lactam structure of Ceftriaxone Sodium Powder acts on the carboxypeptidase, peptide chain endonuclease and transpeptidase of bacterial cell plasma membrane, all these enzymes are involved in cell synthesis and cell division, through these lead to cell wall defects and cell death, inhibit the mucopeptide synthesis of bacterial cell wall to achieve therapeutic effect, in the treatment of lower respiratory tract infection, skin tissue, urinary tract infection, Bone and joint infections and bacterial sepsis have achieved good therapeutic results.

Ceftriaxone Sodium Powder is used for the prevention of lower respiratory tract infections, urinary tract and biliary tract infections, as well as abdominal infections, pelvic infections, skin and soft tissue infections, bone and joint infections, sepsis, meningitis, etc. caused by sensitive pathogenic bacteria, and for the prevention of intraoperative infections.

Pharmacological Effects of Ceftriaxone Sodium Powder

Ceftriaxone Sodium Powder is a third generation cephalosporin antibiotic. It has potent activity against Enterobacteriaceae bacteria. The MIC90 against Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Bacillus flurodii citrate, Indole-positive Aspergillus, Prevotella spp. and Serratia spp. ranged from 0.12 to 0.25 mg/L.

Enterobacter cloacae, Bacillus immobilis and Pseudomonas aeruginosa have poor sensitivity to this product. It has strong antibacterial effect on Haemophilus influenzae, Neisseria gonorrhoeae and Neisseria meningitidis, and also has good effect on Streptococcus haemolyticus and Pneumococcus pneumoniae. The MIC for Staphylococcus aureus is 2-4mg/L. Methicillin-resistant Staphylococcus and Enterococcus are resistant to this product. Most Bacteroides fragilis are resistant to this product.

Ceftriaxone Sodium Powder is a 3rd generation cephalosporin antibiotic with broad spectrum and high efficiency. It is bactericidal to many Gram-positive, negative and anaerobic bacteria and is highly stable to most β-lactamases produced by bacteria, which enhances its antibacterial effect.