Clindamycin Hydrochloride Raw Material Clindamycin HCL Powder

CAS: 21462-39-5 

MF: C18H34Cl2N2O5S

MW: 461.44

EINECS: 244-398-6

Specification​: 99% min Clindamycin Hydrochloride

Sample:  Clindamycin Hydrochloride Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Clindamycin Hydrochloride Powder Usage and Synthesis.

Clindamycin Hydrochloride Powder is mainly used clinically for the treatment of infections caused by Gram-positive cocci and various anaerobic bacteria, for the treatment of joint, bone marrow, respiratory and skin soft tissue infections, as well as tonsillitis, pharyngitis, pneumonia, for acne, gynecological inflammation, endocarditis, abscess chest and other various infections. 

Clindamycin Hydrochloride Raw Material is easy to dissolve, has a high distribution coefficient in the body, has few adverse effects, and is not affected by daily diet.Clindamycin Hydrochloride CAS 21462-39-5 is a semi-synthetic antibiotic with a broad antibacterial spectrum. Antimicrobial agents. The antimicrobial spectrum is similar to that of Zithromax.

Clindamycin should be given intravenously for severe infections, especially anaerobic infections, and high dose rapid drip is contraindicated. It should not be combined with ampicillin, phenytoin, barbiturates, aminophylline, calcium gluconate, magnesium sulfate, macrolides such as erythromycin, dactinomycin, methicillin and chloramphenicol, or with sodium sulfadiazine and vitamin C in the same container.

Clindamycin Hydrochloride Raw Material has a synergistic effect with gentamicin and can be used in combination with TMP to improve clinical treatment and reduce adverse drug reactions. It can be successfully used in combination with antibacterial drugs such as amikacin, tobramycin, methicillin, cephalosporins and fluoroquinolones. The most serious adverse reaction is pseudomembranous enteritis, which can occur during treatment or several weeks after the drug is administered, and once it occurs, it can be treated with vancomycin. Other gastrointestinal reactions include nausea, bloating, anorexia, diarrhea, etc. The incidence is 2%-20%.

Uses and functions of Clindamycin Hydrochloride Powder.

1. Antimicrobial agents. The antibacterial spectrum is similar to that of jessamycin.
2. Clindamycin Hydrochloride Powder is a semi-synthetic antibiotic obtained by replacing the hydroxyl group at the 7 position of clindamycin with a chlorine atom. 
3. Clindamycin hydrochloride is a derivative of lincomycin, and its bactericidal activity against Staphylococcus aureus and pneumococcus is many times stronger than that of lincomycin.

Pharmacological Effects of Clindamycin Hydrochloride Powder.

• Clindamycin Hydrochloride Powder is a semi-synthetic antibiotic with a broad antibacterial spectrum and strong antibacterial activity. It has significant antibacterial activity against gram-positive bacteria and can effectively kill staphylococci, anaerobic bacteria, pneumococci and streptococci. It is active against pathogenic parasites such as Pneumocystis carinii, Toxoplasma gondii and Plasmodium falciparum, and has little adverse effects. 
• Clindamycin Hydrochloride Powder products currently used in clinical practice include clindamycin hydrochloride, clindamycin phosphate and clindamycin palmitate, of which clindamycin phosphate and clindamycin palmitate have no antibacterial activity of their own and exert antibacterial and antiparasitic effects after metabolism to clindamycin in the body. Clindamycin hydrochloride is a derivative of lincomycin. 
• Clindamycin hydrochloride has a broader antibacterial spectrum than lincomycin, and its antibacterial activity is 4-8 times higher than that of lincomycin. It has antibacterial activity against Gram-positive aerobic bacteria, Staphylococcus and Streptococcus, and also against Mycoplasma, Chlamydia and many anaerobic bacteria.

Production method of Clindamycin Hydrochloride Powder

Clindamycin is a derivative of jessamycin, which is a semi-synthetic antibiotic obtained by replacing the hydroxyl group at the 7 position of jessamycin with a chlorine atom.