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Pranlukast Raw Material Pranlukast Powder
Product Overview:
Manufactory Supply Pranlukast Raw Material , High Purity 99% Pranlukast Powder CAS 103177-37-3 Pranlukast Raw Material is a commonly used respiratory drug that belongs to the class of asthma medications. Pranlukast Raw Powder is clinically used for the prevention of bronchial asthma.
Pranlukast Raw Material Pranlukast Powder Attributes
Brand: Henrikang
Appearance: White Powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Specification: 99%min Pranlukast Hydrate
Test Method: HPLC
CAS: 103177-37-3
MF: C27H23N5O4
Sample: Pranlukast Hydrate Powder
Keywords: Pranlukast, Pranlukast Hydrate Powder, Pranlukast Raw Material, Pranlukast Supplier
Pranlukast Raw Material Pranlukast Powder Details
Pranlukast is a commonly used respiratory drug, an antiasthmatic, and a cysteamine leukotriene (LTs) receptor antagonist, which selectively binds to LTC4, LTD4, and LTE4 receptors to antagonize their effects.
Function and application with Zarustra. It is clinically used to prevent bronchial asthma. 225mg orally once, twice a day, after breakfast and dinner.
After taking the drug, there may be gastrointestinal reactions, including nausea, vomiting, abdominal pain, diarrhea or constipation, and sometimes fever, rash, pruritus, elevated serum aminotransferase or bilirubin and other abnormal liver function.
Pregnant women use with caution, the elderly should be appropriate to reduce the amount. This product does not relieve the onset of asthma.
Pharmacokinetics:
Pranlukast 225mg orally, about 3 hours after the peak blood concentration, the effect can last for 12 hours. Fasting drug is absorbed faster than postprandial drug. Plasma protein binding rate of Prenast > 99%.
Nocturnal administration has higher bioavailability than early morning administration, so it is suitable for bedtime administration. It can be used as a daily medication to treat asthma. Age had no significant effect on drug metabolism.
Anti-asthma effect:
Both animal studies and human studies have shown that Prenast can effectively inhibit airway constriction induced by leukotriene, and can not antagonize airway constriction induced by histamine and acetylcholine, indicating that prenast is a specific leukotriene receptor antagonist. It is also effective for cold air induced bronchoconstriction and aspirin induced asthma.
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