Furosemide for Edema and Hypertension

Furosemide for Edema and Hypertension

Furosemide is a strong, short-acting circulating diuretic that acts mainly on the kidneys to increase the excretion of sodium and potassium ions and water. In patients with acute heart failure, intravenous administration of furosemide produces an effective vasodilating effect before the onset of diuretic effect, which can rapidly increase systemic venous volume, lower left ventricular filling pressure and reduce pulmonary edema.

Furosemide Powder, also known as furanilic acid, tachyphylaxis, tachyphylaxis, diuretic, diuretic sulfonamide, abdominal anhydrous acid, Furosemide CAS 54-31-9 is an aminosulfonyl high potency diuretic that acts on the ascending medulla of medullary collaterals, with strong and transient diuretic effect, Furosemide Raw Material is clinically used to treat cardiac Furosemide Raw Material is clinically used to treat cardiac edema, renal edema, cirrhotic ascites, peripheral edema caused by dysfunction or vascular disorders, and to promote the discharge of upper urethral stones. Its diuretic effect is rapid and powerful, and it is mostly used in severe cases where other diuretics are ineffective.

What are the indications for furosemide?

(1) Edematous diseases

Including congestive heart failure, liver cirrhosis, renal diseases (nephritis, nephropathy and acute and chronic renal failure due to various reasons).

Especially when the application of other diuretics is not effective, the application of this class of drugs may still be effective.

Combined with other drugs to treat acute pulmonary edema and acute cerebral edema, etc.

(2) Hypertension

Furosemide can lower blood pressure by excreting sodium and chloride to reduce peripheral vascular resistance and extracellular volume, and eventually achieve the purpose of lowering blood pressure.

However, it is not used as the first choice for the treatment of primary hypertension, and it is especially suitable when thiazides are not effective, especially when accompanied by renal insufficiency or hypertensive crisis.

(3) Prevention of acute renal failure

For various causes of renal perfusion deficiency, such as water loss, shock, poisoning, anesthesia accident and circulatory insufficiency, etc., timely application while correcting blood volume deficiency can reduce the chance of acute renal tubular necrosis.

(4) Hyperkalemia and hypercalcemia.

(5) Dilute hyponatremia (especially when the blood sodium concentration is below 120 mmol/L).

(6) Antidiuretic hormone hypersecretion disorder.

(7) Acute drug toxicity (e.g., barbiturate poisoning).