Ausreson API Fenbendazole Ivermectin capsules 222mg 444mg for Anti-Cancer

Dosage Form:capsules

Dose:2 capsules per day

Type of Product:Fenbendazole capsules

Model Number:ARN-Fenbendazole capsules

Specification: customize

Sample:Fenbendazole capsules Avaliable

Keywords:Fenbendazole capsules

Brand: Ausreson

Appearance:capsules

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Benefits of Fenbendazole capsules.

Antiparasitic effect ‌

By inhibiting the synthesis of parasite microtubule proteins, interfering with the energy metabolism of the parasite (such as blocking glucose uptake), leading to the death of the parasite

It has a significant killing effect on nematodes (ascaris, hookworms, whipworms) and some tapeworms (such as Dipylidium caninum)

‌Broad-spectrum and safety ‌

It is well tolerated by host animals such as dogs and cats at therapeutic doses, with few side effects

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How to use fenbendazole capsules correctly?

1. Applicable objects and uses

‌Main uses‌: Used to treat intestinal parasites such as roundworms, hookworms, and tapeworms in pets such as dogs and cats. It also has an auxiliary effect on some external parasites (such as mites)

‌Applicable animals‌: Suitable for puppies/cats over 2 weeks old and with a weight that meets the standard. Pregnant animals must strictly follow the doctor's instructions

2. Dosage and usage

‌Conventional dose‌

‌Dogs‌: Calculated at 25-50 mg per kilogram of body weight, once a day, for 3 consecutive days (tapeworm infection may need to be extended to 7 days)

‌Cats‌: 20-100 mg per kilogram of body weight, the course of treatment is adjusted according to the type of parasites (such as nematode infection requires 5 consecutive days)

‌Adjustments for special groups‌

Pregnant female dogs are recommended to reduce the dose to 25 mg/kg, and continue to use the drug from 40 days of pregnancy to 2 days after delivery

Animals with impaired liver and kidney function The dose needs to be reduced or the dosing interval needs to be extended

III. Precautions for taking medicine

‌Dosing time‌: It is recommended to take it on an empty stomach (1 hour before or 2 hours after a meal) to enhance absorption

‌Dosage method‌: It can be taken directly orally or crushed and mixed with food, and sufficient intake must be ensured

‌Treatment cycle‌: Generally, repeated medication is required (2-4 weeks apart), and preventive deworming is done every 3 months

IV. Contraindications and side effects

‌Contraindications‌: It is contraindicated for animals in early pregnancy, individuals with severe liver and kidney dysfunction, and those who are allergic to the drug

‌Common side effects‌: It may cause vomiting, diarrhea, or decreased appetite. If symptoms persist, the drug should be discontinued and medical attention should be sought

V. Drug interactions

Avoid combined use with other anthelmintics such as praziquantel and ivermectin, which may increase the risk of toxicity

Animals that use glucocorticoids for a long time need to be evaluated before deciding whether to use them together

Application of Fenbendazole capsules. 

Veterinary field ‌

‌Applicable animals‌: Treatment of intestinal parasitic infections in dogs, cats, horses, cattle and other livestock and companion animals

‌Usage‌: Precise dosing according to body weight (25-50 mg/kg for dogs, 20-100 mg/kg for cats), usually for 3-5 consecutive days

‌Potential research direction‌

Laboratory studies have shown that it may inhibit cancer cells by stabilizing HIF-1α and other mechanisms, but it has not yet been approved for human cancer treatment.

How fenbendazole capsules work.

1. Core anti-parasitic mechanism

‌Tubulin inhibition‌

Selectively binds to the parasite's β-tubulin, blocking its polymerization to form microtubule structures, leading to cytoskeleton collapse

By destroying microtubule-dependent functions (such as nutrient transport and cell division), the parasite loses its ability to move and dies

‌Energy metabolism interference‌

Inhibits glucose uptake by the parasite, deprives it of its energy source, and accelerates the exhaustion of the parasite

It has a specific damaging effect on the epidermal cells of the digestive system of nematodes (such as roundworms and hookworms) and some tapeworms

2. Potential anti-cancer mechanism (research stage)

‌Microtubule stability regulation‌

Similar to paclitaxel, it inhibits mitotic spindle formation and blocks cell division by stabilizing cancer cell microtubules

May inhibit the adaptability of the tumor microenvironment by interfering with the HIF-1α pathway

‌Multi-target effect‌

Induce cancer cell apoptosis and have synergistic potential with traditional chemotherapy drugs (such as vinca alkaloids)

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