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china manufacturer honokiol extract powder supplier factory

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Product Overview:

Honokiol Raw Material Factory Supply Honokiol Nutritional Supplement Honokiol Powder Raw Material, High Quality Honokiol Powder Purity 99% Honokiol Powder Osthole Nutritional Supplements. Honokiol Raw Material is known as neolignan, which is found more in camphor plants, and is an active ingredient in the Chinese traditional medicine Houpao as an antibacterial and anti-inflammatory agent.

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china manufacturer honokiol extract powder supplier factory Attributes

Honokiol Raw Material Honokiol Powder

CAS: 35354-74-6

MF: C18H18O2

和厚朴酚结构式

MW: 266.33

EINECS: 609-119-8

Specification: 99% min Honokiol powder

Packaging: 1kg/bag. 25kg/bag

Brand: Ausreson

MOQ:1kg

Keywords:high purity honokiol

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

china manufacturer honokiol extract powder supplier factory Details

Product Name	Organic magnolia officinalis bark extract powder 8%~95% Magnolol/Honokiol
Latin Name	Magnolia officinalis P.E.
Appearance	White powder
Source	Naringin peel
Keywords	Magnolia officinalis P.E. Extract ; Magnolia officinalis P.E. Extract powder; Organic Magnolia officinalis P.E.Extract
Storage	Store in cool &dry place,keep away from strong light and heat.
Shelf Life	24 Months
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Honokiol Raw Material Powder Usage and Synthesis

Manufactory Supply Honokiol Powder Raw Material, High Purity Honokiol Powder Nutritional Supplement Honokiol Raw Powder, High Quality Honokiol Powder.Fournisseur de poudre de honokiol de haute pureté issu de l'extrait d'écorce de magnolia

Uses and functions of Honokiol Powder

And Houpaku phenol for Houpaku phenol isomer, is by a phenylpropanoid side chain and another phenylpropanoid benzene nucleus polymerisation and become a dimer, called the so-called new lignans, in the camphor plant found more, for the traditional Chinese medicine Houpaku antimicrobial and anti-inflammatory active ingredient.Lieferant von hochreinem Honokiol-Pulver aus Magnolienrinden-Extrakt

Bioactive pharmacological effects of Honokiol Raw Powder

Houpu Decoction has an inhibitory effect on Gram-positive bacteria such as staphylococcus, haemolytic streptococcus, pneumococcus, pertussis bacillus and Gram-negative bacteria such as anthrax bacillus, dysentery bacillus, typhoid bacillus, paratyphoid bacillus, Vibrio cholerae, E. coli, Aspergillus spp., bacillus subtilis and Corynebacterium leprae, with the strongest inhibition on staphylococcus.Fornecedor de pó de honokiol de alta pureza a partir de extrato de casca de magnólia

Honokiol vs MagnololПоставщик порошка гонокиола высокой чистоты из экстракта коры магнолии

Characteristics	Magnolol	Magnolol
Chemical Structure	Two benzene rings connected by a C-C bond, with hydroxyl groups in ortho and para positions.	Two benzene rings connected by a C-C bond, with both hydroxyl groups in ortho positions.
Physical Properties	Slightly more hydrophilic, higher polarity.	More lipophilic, lower polarity.
Biological Activity Strength and Characteristics	More potent and broader spectrum: • Anti-anxiety/Sedation: Highly effective as a GABA receptor modulator, though sedative effect is weaker than magnolol. • Anticancer: Exceptionally potent in inducing cancer cell apoptosis, effective against multiple cancer cell lines. • Neuroprotection: Protects neurons from damage, promotes nerve regeneration, and exhibits exceptional blood-brain barrier penetration. • Cardiovascular protection: Anti-arrhythmic and myocardial protective.	Relatively mild with specific emphases: • Anti-anxiety/Sedation: Exhibits sedative effects, though research focus differs slightly. • Antioxidant: Powerful free radical scavenger. • Antimicrobial: Effective against bacteria like Propionibacterium acnes and fungi, commonly used in skincare products. • Gastrointestinal protection: Anti-ulcer and regulation of intestinal motility. • Antiplatelet aggregation: Prevents thrombus formation
Mechanism of Action	Targets a diverse range of pathways, including: • Modulation of GABA receptors • Activation of signaling pathways like AMPK and SIRT3 • Inhibition of inflammatory pathways such as NF-κB	Mechanisms overlap with magnolol but also differ: • Modulation of cannabinoid (CB2) receptors • Action as an estrogen receptor beta (ERβ) agonist • Also inhibits pathways like NF-κB
Pharmacokinetics	Well absorbed orally, rapidly crosses the blood-brain barrier, achieving high concentrations in brain tissue. This is key to its neuroactive properties.	Absorbed well, but blood-brain barrier penetration is weaker than magnolol.
Primary Applications	• Dietary supplements (for anti-anxiety, mood enhancement) • Potential adjuvant anticancer agent • Research on neurodegenerative diseases (e.g., Alzheimer's disease) • Research on cardiovascular diseases	• Skin care products (for acne treatment, anti-inflammatory effects, antioxidant properties) • Oral care products (antibacterial, anti-inflammatory) • Gastrointestinal health products • Also has applications such as anti-anxiety effects

In 15% concentration on the experimental animals of small spores of ringworm, concentric trichophyton, red trichophyton, beautiful colour trichophyton and other skin fungi have inhibition. The decoction of Houpu has certain effects on improving substantial pathological damage in experimental viral hepatitis in mice.

Magnolol and its hydroxymethyl derivatives showed significant inhibitory effects on stage II skin tumours in mice. The three extracted constituents lignans in Hauppauge.

thujaplicin, and thujaplicinol and the monoterpene xylenol were antagonists of 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced activation of Epstein-Barr virus early antigen (EBv-EA).

The methanol extract and thujaplicin of A. thujaplica showed significant inhibitory effects on mouse skin tumours induced by in vivo phase II carcinogenicity assays.

FAQ.

Q: What is the difference between Honokiol and Magnolol? How should one choose between them?

A: Honokiol and Magnolol are two primary active compounds coexisting in Magnolia officinalis, sharing structural similarities but exhibiting distinct pharmacological activities. Honokiol demonstrates stronger or unique potency in anti-anxiety, neuroprotection, and anti-tumor effects, coupled with higher bioavailability. If your research objectives specifically target these areas, high-purity Honokiol Powder is the preferred choice. We also offer mixed reference standards with varying ratios of Honokiol and Magnolol.

Q: Can your products be used for commercial production of dietary supplements?

A: Yes. Our high-purity Honokiol Powder is ideal for premium dietary supplement formulations, ensuring product efficacy and safety. We provide all necessary documentation to support its compliant use as a dietary ingredient under the DSHEA regulations in the United States. Please note that responsibility for the final product lies with the brand owner.

Q: What is the minimum order quantity (MOQ)? Do you support R&D-grade sample purchases?

A: We fully understand R&D requirements and can accommodate MOQs as low as 1 gram. We offer flexible small packaging options for researchers and startups worldwide, and provide evaluation samples for promising collaborative projects.

Q: How can the water solubility issue of Honokiol be addressed?

A: Poor water solubility of Honokiol is a common challenge in formulation development. We offer Honokiol formulation solutions based on advanced technologies such as cyclodextrin inclusion complexes and nanocrystalline technology.

Our Strengths

Henrikang possesses the capability to produce any capsule formulation. From sourcing every ingredient in the formula to post-filling inspection, we handle the entire process at optimal pricing and with the fastest delivery times.

With extensive experience, we can assist you in developing new products for your target audience or discuss how to scale up production efficiently. As your partner, we are committed to achieving long-term success in capsule manufacturing.

As a leading OEM manufacturer of nutritional supplement ingredients and branded products in China, we hold certifications including ISO 22000, ISO 9001, HACCP, GMP, Halal, CE, CE-ROHS, Kosher, SGS, Intertek, Eurofins, and GMP. Our facility has passed FDA inspection and completed registration.