Thiamine Hcl Raw Materials Thiamine Hcl Powder

CAS:67-03-8

MF:C12H17N4OS.ClH.Cl

MW:337.27

EINECS:200-641-8

Specification: 99% min Thiamine Hcl Powder

Sample:Thiamine Hcl Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White to Off-White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Thiamine Hcl Powder Usage and Synthesis.

Vitamin B1 plays an important role in maintaining normal nerve conduction, the heart, and the normal activity of the digestive system. When it is deficient, it is easy to suffer from foot fungus or polyneuritis and other diseases.

China's regulations can be used in infant food, the use of 4 ~ 8mg / kg; in cereals and their products in the use of 3.0 ~ 5.0mg / kg; in the drinking liquid, milk drinks, the use of 1 ~ 2mg / kg. This product can be used for thiamine nitrate fortification, the specific dosage must be converted. This product plays an important role in sugar metabolism.

It plays an important role in sugar metabolism.

The energy of nerve tissue is mainly supplied by sugar metabolism, once the lack of vitamin B1 is produced, the energy supply is impaired, and lactic acid and pyruvic acid accumulate, resulting in polyneuritis, which manifests sensory abnormalities, limb weakness, neuromuscular aches and pains and atrophy, and at the same time, cardiac metabolism is dysregulated, and there are symptoms of cardiomyopathic insufficiency, such as palpitations, chest tightness, cardiac hypertrophy, hepatic stasis, and peripheral oedema.

Vitamin B1 mild deficiency is listed as loss of appetite with weight loss and debility.

It is used for vitamin B1 deficiency, high fever, hyperthyroidism, large amount of glucose input, systemic infection, diabetes mellitus and polyneuritis.

Uses and functions of Thiamine Hcl.

Vitamin B1 plays an important role in maintaining normal nerve conduction, the heart, and the normal activity of the digestive system. When lacking, it is easy to suffer from foot fungus or polyneuritis and other diseases.

China's regulations can be used in infant food, the use of 4 ~ 8mg / kg; in cereals and their products in the use of 3.0 ~ 5.0mg / kg; in the drinking liquid, milk drinks, the use of 1 ~ 2mg / kg. This product can be used to thiamine nitrate fortification, the specific dosage must be converted.

Function of Thiamine Hcl.

Thiamine Hydrochloride is a form of Vitamin B1,USES: Nutritional supplement. Vitamin B1 is involved in the intermediate metabolism of sugars in the body.

Insufficient vitamin B1 in the organism, coenzyme carboxylase activity decreases, sugar metabolism is blocked, thus affecting the entire body metabolic process. Among them, acetone decarboxylation is blocked, which cannot enter the tricarboxylic acid cycle, does not continue to oxidise, and accumulates in the tissues.

At this time, the nerve tissue supply is insufficient, so the corresponding neuromuscular symptoms can appear, such as polyneuritis, muscle atrophy and oedema, and in severe cases can also affect the function of the heart muscle and brain tissue.

Vitamin B1 deficiency can also cause indigestion, loss of appetite and constipation.

Product Method of  Bulk Thiamine Hcl Powder.

Vitamin B1 occurs naturally in foods such as rice bran, bran, lean meat, and peanut rice, and in pure form is usually prepared by chemical synthesis.

Excess acetamidine hydrochloride is condensed with α-dimethoxy-β-methoxypropionitrile in an alkaline (methanol and sodium methanol) medium to 3,6-dimethyl-1,2-dihydro-2,4,5,7-tetraazanaphthalene, which is then hydrolysed at 98-100°C, then ring-opened to form 2-methyl-4-amino-5-aminomethylpyrimidine in alkaline conditions; this is followed by interaction with carbon disulphide and ammonia, and then with acetic acid -γ- Chloro-γ-acetylpropyl acetate, then hydrolysed and ring-opened in hydrochloric acid at 75-78°C to form thiosulfamide hydrochloride, and finally thiamine hydrochloride was obtained by neutralisation with ammonia, oxidation with hydrogen peroxide and acidification with hydrochloric acid.