Food Additive Vitamin B6 Powder

CAS:8059-24-3

MF:C10H16N2O3S

MW: 244.31

EINECS:232-503-8

Specification​: 99% min Vitamin B6Powder

Sample:Vitamin B6 Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Vitamin B6 Powder Usage and Synthesis.

Vitamin B6, also known as the "anti-dermatitis vitamin", is one of the B vitamins. It is a pyridine derivative, including pyridoxine, pyridoxal and pyridoxamine, which exist in food in the form of interconversion.

However, vitamin B6 in plants is mostly pyridoxal, while in humans and animals it is mostly pyridoxal and pyridoxamine. Human intestinal bacteria can also synthesise pyridoxine, and in humans pyridoxine can be converted to pyridoxal and pyridoxamine, while the latter two cannot be converted to pyridoxine.

All three have the same physiological activity.

Vitamin B6 is rapidly converted to pyridoxal phosphate in the human body, and this compound plays an important role in amino acid metabolism, as a coenzyme for decarboxylase, transaminase, kynurenine enzyme, deaminase, desulfhydrase.

It is also an essential coenzyme for carbohydrate and fat metabolism, central nervous system activity and haemoglobin production.

Vitamin B6 is widely found in nature, egg yolks, fish, meat, seeds, cereals (germ) content is more, the general diet is not deficient in this vitamin. Lack of vitamin B6 can cause dermatitis, cramps, anaemia and other symptoms.

Vitamin B6 is mainly used in pregnancy, radiation disease and anticancer drugs caused by vomiting, vitamin B6 deficiency, seborrheic dermatitis, lipitis, keratitis and acute and chronic eczema, etc., but also can be used in food fortification, feed additives and cosmetics.

Uses and functions of Vitamin B6.

(1)It is suitable for the treatment of vitamin B6 deficiency (vitamin B6 deficiency can cause xanthuric aciduria, iron-granulocyte anaemia, neurological lesions, seborrheic dermatitis and chapped lips), and for the treatment of isoniazid poisoning; it can also be used for vomiting and seborrheic dermatitis caused by pregnancy, radiation sickness and anticancer drugs.

(2)Total gastro-intestinal nutrition and

Vitamin B6 supplementation for malnutrition and progressive weight loss due to insufficient intake.

(3) Treatment of infantile convulsions or administration to pregnant women to prevent infantile convulsions.

(4) Leukopenia.

Pharmacological effect of Vitamin B6.

In the body and ATP by enzymatic action can produce active pyridoxal and pyridoxamine phosphate, the latter as a coenzyme for proteins, carbohydrates, lipids play a role in various metabolic functions.

Vitamin B6 is also involved in the conversion of tryptophan into niacin or 5-hydroxytryptophan.

In the gastrointestinal mainly absorbed by the jejunum, pyridoxamine phosphate and plasma protein binding completely, T1/2 up to 15 ~ 20 days, through the liver metabolism, excretion through the kidneys, can also be excreted through haemodialysis.

The first step in haemoglobin synthesis is the linkage of glycine to pyridoxal phosphate converted from vitamin B6, and then to succinate-coenzyme A, which is combined with α-aminopropionylacetate synthetase to form α-amino-γ-ketoglutarate (ALA). and then

After a series of enzymes, protoporphyrin is finally formed in the mitochondria. Iron enters the porphyrin ring and binds to the protoporphyrin to become haemoglobin.

Reduce the stimulation of emetic chemoreceptors, reduce nausea, vomiting and other symptoms, and can promote the growth of white blood cells. Topical application improves local nerve function and reduces inflammatory reactions.

Adverse Reaction of Bulk Vitamin B6 Powder.

Vitamin B6 produces little or no toxicity in people with normal renal function. If 200mg a day is taken for more than 30 days, vitamin B6 dependence syndrome has been reported.

Taking 20-60g a day for several months can cause severe neurosensory abnormalities, progressive gait instability to numbness of the feet, and dexterity of the hands, which resolves when the drug is discontinued.

Occasionally, allergic reactions such as rash and anaphylaxis are seen. Occasionally, skin irritation such as burning sensation, or allergic reactions such as rash and itching.