Nicotinic acid Raw Materials Nicotinic acid Powder

CAS:59-67-6

MF:C6H5NO2

MW:123.11

EINECS:200-441-0

Specification: 99% min Nicotinic acid Powder

Sample:Nicotinic acid Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White to Off-White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Nicotinic acid Powder Usage and Synthesis.

Niacin is a precursor of the coenzymes NAD and NADP. It is widely distributed in nature and is found in abundance in liver, fish, yeast and cereals. Dietary deficiencies have been associated with pellagra. The term "niacin" is also used for niacinamide or other derivatives with niacin bioactivity. Vitamin (enzyme cofactor).

Niacin is mainly used as feed additives, which can improve the utilisation rate of feed protein, milk production of dairy cows and meat production and quality of fish, chickens, ducks, cows, sheep and other livestock.

Nicotinic acid is also a widely used pharmaceutical intermediates, with its raw materials, can be synthesised into a variety of pharmaceuticals, such as nicosamide and nicotinic acid inositol ester.

In addition, nicotinic acid also plays an irreplaceable role in luminescent materials, dyes, electroplating industry and other fields.

Uses and functions of Nicotinic acid.

This product is a vitamin drug, and niacinamide collectively known as vitamin PP, used for anti-hirsutism, can also be used as blood expansion drugs, a large number of food and feed additives.

As a pharmaceutical intermediate, it is used in the production of isoniazid, nicotinamide, nicosamide and inositol nicotinate.

Niacin is an important hydrogen transporter and anti-mange factor in the organism, maintains the health of skin and nerves, and promotes the role of digestion. Dosage 30-80mg/kg.

Niacin is an important hydrogen transporter and anti-mange factor in organism tissues, maintaining skin and nerve health and promoting digestion.

China's regulations can be used to fortify cereals and their products, the use of 40-50mg/kg; in the fortification of baby food use 30-40mg/kg; in the drinking liquid and milk drinks use 10-40mg/kg.

In addition, it can be used as feed additives and colouring auxiliaries for meat products.

Function of Nicotinic acid.

Constitutes nicotinamide adenine dinucleotide (Coenzyme I, NAD+ or CoI) and nicotinamide adenine dinucleotide phosphate (Coenzyme 11, NADP+ or CoII) Nicotinamide binds to adenine, ribose, and phosphoric acid in vivo to constitute nicotinamide adenine dinucleotide and nicotinamide adenine dinucleotide phosphate, which act as electron carriers or hydrogen transporters in biological redox reactions that depend on molecular structure Nicotinamide part.

The nicotinamide pyridine ring has reversible hydrogen- and electron-addition and dehydrodegeneration properties, transferring hydrogen and electrons during enzymatic reactions. Glucose Tolerance Factor (GTF) is a complex of trivalent chromium, niacin, and glutathione, and is an insulin cofactor that increases glucose utilisation and promotes the conversion of glucose to fat.

Niacin reduces blood cholesterol, triglyceride and beta-lipoprotein concentrations and dilates blood vessels.

Product Method of  Bulk Nicotinic acid Powder.

It is obtained from 3-methylpyridine by oxidation and acidification. Another method using 3-methylpyridine as feedstock is gas phase oxidation with ammonia. Using a fluidised bed reactor, 3-methylpyridine, air and ammonia are mixed proportionally and reacted at 290-360 under the action of a vanadium catalyst.

The fumonisole obtained was hydrolysed with sodium hydroxide at 160°C. If the hydrolysis is carried out with ammonia, the solubility of the hydrolysis is controlled to obtain nicotinic acid or nicotinamide, respectively. Nicotinic acid can also be produced from nicotine (tobacco).

Fluidised bed reactor is used, with ferric ammonium citrate as catalyst, and gas phase oxidation with air at 65-105 °C.

Nicotinic acid can also be produced industrially from quinoline, which is commonly oxidised and decarboxylated by ozone or oxidised and decarboxylated by nitric acid.