Ginkgo Biloba Extract Raw Materials Powder

CAS:90045-36-6

MF:/

MW:/

EINECS:289-896-4

Specification: 99% min Ginkgo Biloba Extract Powder

Sample:Ginkgo Biloba Extract Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Brown

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Ginkgo Biloba Extract Powder Usage and Synthesis.

Ginkgo biloba extract is an active ingredient extracted from Ginkgo biloba, which has a variety of pharmacological effects. Firstly, Ginkgo biloba extract can inhibit the activity of angiotensin-converting enzyme, thus dilating blood vessels and increasing blood flow, which plays a role in lowering blood pressure.

Secondly, Ginkgo biloba extract improves atherosclerosis, reduces the formation of neoplastic endothelium, and has a therapeutic effect on diabetes. In addition, Ginkgo biloba extract improves cerebral circulatory metabolism and promotes memory function.

Therapeutically, Ginkgo biloba extract can be used either orally or by injection, and injections should be made according to a doctor's recommendation. It should be noted that Ginkgo biloba extract should be contraindicated in people who are allergic to it.

Uses of Ginkgo Biloba Extract.

1. Acute and chronic cerebral insufficiency and its sequelae: stroke, inattention, memory loss, dementia.

2, ear blood flow and nerve disorders: tinnitus, vertigo, hearing loss, ear labyrinth syndrome.

3, eye blood flow and nerve disorders: retinopathy and nerve disorders caused by diabetes, age-related macular degeneration, blurred vision, chronic glaucoma.

4, peripheral circulatory disorders: various arterial occlusive disease, intermittent claudication, paralysis and cold hands and feet, limb pain.

Extraction method of Ginkgo Biloba Extract.

1. Ethanol extraction - large pore resin adsorption separation method

Pick off impurities and mouldy leaves, wash, chop, reflux extraction with 70% ethanol, extract, filter, decompression recovery of ethanol, high-speed centrifugation to remove slag, dilute with appropriate amount of pure water, add to the macroporous adsorption resin column, water elution to the eluent is clear and bright light, and then a certain concentration of ethanol elution, collection of the eluent, concentration under reduced pressure, vacuum drying that is obtained.

2. Acetone extraction - lead hydroxide precipitation method

Ginkgo biloba extracted with 60% acetone, cooled and filtered, extracted with carbon tetrachloride, add butanone and mixing, separation and precipitation of acetone - butanone phase, in the ketone phase and then add solid ammonia sulfate stirring, filtered solids, evaporation filtrate under reduced pressure to the concentration of 20% -60% of the solids, diluted to the concentration of 50% denatured ethanol to the concentration of 10% of the solids. Add a suspension of lead hydroxide and filter off the precipitate.

Concentrate the filtrate to half volume under reduced pressure, then add ammonia sulphate and butanone to the concentrate under stirring, and precipitate the butanone-ethanol phase at the end of stirring; separate the butanone-ethanol phase from the aqueous phase, and then add butanone to the aqueous phase, stirring, and precipitate the butanone-ethanol phase, which is combined in the above butanone-ethanol phase.

Add ammonia sulphate under stirring, mix and separate the precipitated aqueous phase, dry the butanone-ethanol phase with sodium sulphate, evaporate to dryness under reduced pressure, dissolve the denatured viscous residual liquid with denatured ethanol, leave for 12 hours to separate the precipitate precipitated, evaporate under reduced pressure, and dry in vacuum to obtain.

Pharmacological Effect of  Bulk Ginkgo Biloba Extract Powder.

1.Anti-aging effect

Ginkgo biflavones, isoginkgo biflavones, ginkgetin and quercetin in Ginkgo biloba have inhibited lipid peroxidation, especially quercetin has stronger inhibitory activity.

2.Role in transplant rejection and other immune reactions

Ginkgo biloba extract can prolong the survival time of transplanted skin, ectopic heart xenograft, orthotopic liver xenograft. Ginkgo biloba extract can inhibit the body's natural killer cell activity against KC526 target cells, and also block the natural killer cell activity caused by interferon.

3.Anti-tumour effects

Ginkgo biloba green leaf crude extract that is fat-soluble part can inhibit the EB virus, seventeen carbene salicylic acid, white fruit flavin (Bilo-betin) have strong inhibitory activity; ginkgo biloba total flavonoids can increase the weight of the thymus of the tumor-bearing mice and the level of SOD activity, mobilising the body's intrinsic anti-tumor ability; quercetin and poplar plum flavin can inhibit the occurrence of carcinogens.

4.Antioxidant effect

Ginkgo biloba extract can directly scavenge lipid free radicals, lipid peroxidation radicals and alkyl radicals, etc., and terminate the chain reaction chain of free radicals. It can also participate in regulating and improving the activity of antioxidant enzymes such as peroxide dismutase, glutathione peroxidase and other antioxidant enzymes.

The antioxidant effect of flavonoids in EGB even exceeds that of vitamins, and they have anti-free radical attack properties in vitro.