Raw Materials Arachidonic acid Powder

CAS:506-32-1

MF:C20H32O2

MW:304.47

EINECS:208-033-4

Specification: 99% min Arachidonic acid Powder

Sample:Arachidonic acid Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Arachidonic acid Powder Usage and Synthesis.

1.Regulate cardiac excitabilityRecently, it has been reported that arachidonic acid and its metabolites, such as LTC4, can activate the cardiac and G-protein-coupled toxocarbocyanine-like K+ channels in a receptor-independent manner, and regulate cardiac excitability in both physiological and pathological conditions.

2. Involved in neuroendocrine arachidonic acid can stimulate the secretion of anterior pituitary, placenta and mast cells, and participate in the regulation of the secretion of many hormones and neuropeptides in a variety of neuroendocrine tissues, such as oxytocin, pressin, insulin and glucagon.

3. Promote cell division of arachidonic acid and its metabolites have the effect of promoting cell division, and its metabolites have this effect in smooth muscle cells, fibroblasts and lymphocytes.

4. Inhibit the role of platelet aggregation arachidonic acid and its metabolites can cause vasodilation. Vascular endothelial cells are closely related to arachidonic acid enzyme, which can release vasodilatory factors, relax vascular smooth muscle and dilate blood vessels under certain stimuli. Due to the above physiological functions, arachidonic acid is widely used in cosmetics, medicine and food.

Uses of Arachidonic acid.

Nutritional additive. Stabilizing, anti-peptic ulcer and gastrointestinal dysfunction, acts on the uterus.

Peanut tetraenoic acid is an important substance for the development of human brain and optic nerve, and plays an important role in improving intelligence and enhancing visual acuity.

Arachidonic acid has a series of physiological activities, such as esterifying cholesterol, increasing the elasticity of blood vessels, reducing blood viscosity, and regulating the function of blood cells. Peanut tetraenoic acid has important effects on the prevention of cardiovascular disease, diabetes and tumors.

Raw material for synthesizing prostaglandins. Regulate the permeability of human cell membrane. Important for the brain and nerve development of infants and children, and the development of the optic nervous system.

It also plays an important role in the treatment of coronary heart disease, diabetes and the prevention of cerebrovascular diseases.

Characteristic of  Bulk Arachidonic acid Powder.

Arachidonic acid is found in certain mosses, seaweeds and other plants, as well as in the adrenal glands and liver of pigs and cattle and in herring.

It is catalyzed by different enzyme systems in living organisms to produce important active substances such as prostaglandins, thromboxanes and leukotrienes. There are four double bonds in the molecule, the first of which starts on the 6th carbon atom from the methyl end, belonging to ω-6 type unsaturated fatty acids.

AA is light yellow oily liquid. Soluble in ethanol, acetone, benzene and other organic solvents. mp about 49 ° C; bp169-171 ° C / 19.998Pa; flash point greater than 110 ° C; refractive index of 1.4824; density of 0.922g / ml; iodine value of 333.4.

There are four active hypomethyl groups in the molecule, it is easy to generate free radicals with oxygen. In 21% KOH ethylene glycol, the UV absorption spectrum of isomerization at 180℃ for 15min, there are characteristic absorption peaks at 233nm, 268nm, 315nm, 346nm.

Product Methods of Arachidonic acid.

The mycelium obtained from the fermentation culture of Mortierella alpina, filtered and pressed to obtain about 3% of the dry mycelium, and refined by CO2 supercritical extraction to obtain about 45% of the oil containing AA, and about 20% of the oil containing unsaturated fatty acids such as α-linolenic acid and γ-linolenic acid.