food grade Iron(III) citrate Powder Manufacturer CAS 3522-50-7

CAS: 3522-50-7

MF: C6H8FeO7

MW: 247.97

EINECS: 222-536-6

Specification: 99% min Iron(III) citrate Powder

Sample: Iron(III) citrate powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 kg

Appearance: red powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Iron(III) citrate Powder Usage and Synthesis.

Iron citrate is used medically to dialyze blood and regulate iron levels in patients with chronic kidney disease. It acts on phosphates present in the diet and forms insoluble compounds, thus reducing their absorption by the digestive system.

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Advantages of Ferric Citrate (III) Powder

1. Excellent Bioavailability

Ferric citrate (III) is more easily absorbed and utilized by the body. Citric acid acts as a carrier, helping iron ions cross the intestinal barrier more effectively into the bloodstream. According to research by the European Food Safety Authority (EFSA), this form of iron supplement has bioavailability comparable to ferrous sulfate, but with better tolerability.

2. Gentle Gastrointestinal Tolerance

Many users of traditional iron supplements often complain of side effects such as constipation and nausea. Ferric citrate (III) powder, due to its unique chemical structure, is gentler on the digestive system, reducing the incidence of these adverse reactions. This makes it an ideal choice for those who need long-term iron supplementation.

3. Versatile Applications

In addition to being a dietary supplement, ferric citrate (III) powder can also be used for food fortification. In Europe, it is approved as a food additive (E381) for iron fortification in certain foods. In the United States, the FDA also recognizes its safety as a nutritional supplement.

4. Suitable for Special Populations

• Pregnant and breastfeeding women: Iron requirements increase by approximately 50% during pregnancy, and ferric citrate (III) provides a safe and effective supplementation option.
• Vegetarians and vegans: Non-heme iron from plant-based diets has lower absorption rates; this supplement can help fill the nutritional gap.
• Athletes and active individuals: Iron is involved in oxygen transport and is crucial for physical performance.
• Older adults: Iron absorption may decline with age.

Uses and functions of Iron(III) citrate.

Iron(III) citrate is a component of the structural basis gated by the Escherichia coli outer membrane receptor FecA. Binding of ferric citrate triggers a conformational change in the extracellular loop that closes the outer pocket of FecA.

Iron citrate, also called ferric citrate, is a small reddish-brown transparent flake crystal, or crystalline powder, insoluble in ethanol, dissolves slowly in cold water and readily in hot water.

Iron citrate is an edible citrate, commonly used as an additive or acidifier in food and feed.

In the field of food science, iron citrate is commonly used as food iron fortification, nutritional supplements; in the field of medicine, it can be used as radiopharmaceuticals, used to check iron metabolism and hematopoietic function; it can also be used as feed additives and so on

How to Choose and Use Ferric Citrate (III) Powder

Key Points for Choosing High-Quality Products

• Certification Marks: Look for GMP (Good Manufacturing Practice) certification and third-party testing certificates.
• Purity Standards: Ensure the product is free of heavy metal contamination and harmful additives.
• Source Transparency: Understand the manufacturer's information and the source of ingredients.
• User Reviews: Refer to feedback and experience sharing from real users.

Usage Recommendations

• Optimal Time to Take: Take on an empty stomach or with foods rich in Vitamin C (such as orange juice) to improve absorption.
• Avoid Taking with Substances That Inhibit Absorption: Such as coffee, tea, calcium supplements, and high-fiber foods.
• Dosage Guidelines: Follow the product instructions or the advice of a medical professional. The common dosage in the European and American markets is 15-30mg of elemental iron daily
• Mixing Methods: Easily dissolves in water, juice, or blended into smoothies.

Applications:

Ferric citrate's applications extend far beyond prescription drugs; it is penetrating multiple downstream industries based on product grade (pharmaceutical grade, food grade).

In medical applications, its primary form is oral tablets (such as the brand-name Zerenex), used for phosphorus management and anemia correction in dialysis patients. Additionally, it is used in laboratories as a biochemical reagent, for example, in the preparation of culture media for haploid breeding.

In the food and nutritional supplement industry, food-grade ferric citrate, as a mild iron fortification agent, is used in certain dietary supplements and nutritional formula foods.

Product method of Bulk Iron(III) citrate Powder.

Add ammonia to the iron sulfate solution to produce iron hydroxide precipitate; then filter and wash to no sulfuric acid reaction, then add citric acid and heat to 60 ℃, so that all the precipitate is dissolved; and finally filtered, the filtrate is concentrated to syrupy and coated on a glass plate, and then peeled off by drying at a slight temperature to get a small flake of finished product.

Frequently Asked Questions about Ferric Citrate (III) Powder

Q1: What is the difference between ferric citrate (III) powder and ferrous sulfate?

A: While both provide iron, ferric citrate (III) is generally better tolerated, with fewer side effects such as constipation and nausea. Its absorption efficiency is comparable to ferrous sulfate, but it is gentler on the stomach.

Q2: Can vegetarians use ferric citrate (III) powder?

A: Yes, ferric citrate (III) powder is perfectly suitable for vegetarians and vegans. It is a non-animal-derived iron supplement that helps compensate for the lower iron absorption rates in plant-based diets.

Q3: How do I know if I need an iron supplement?

A: Common symptoms of iron deficiency include fatigue, dizziness, paleness, and shortness of breath. However, these symptoms may also be associated with other health problems. The best approach is to have a blood test (to check serum ferritin and hemoglobin levels) and consult a healthcare professional.

Q4: Will ferric citrate (III) powder stain my teeth?

A: Liquid iron supplements may temporarily stain teeth. To avoid this, it is recommended to take it with a straw or rinse your mouth or brush your teeth immediately after taking it

Q5: Where can I buy high-quality ferric citrate (III) powder in London or New York?

A: In the European and American markets, you can find it in specialty health food stores, large pharmacies, or reputable online retailers. Look for products with third-party testing certifications and transparent ingredient information. Some well-known brands include Solgar, Nature's Way, and NOW Foods.

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