Bulk chitosan powder for 25kg drum supplier

CAS: 9012-76-4

MF: C6H11NO4X2

MW: 161.16

EINECS: 618-480-0

Specification: 99% min Chitosan Powder

Sample: Chitosan Powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 KG

Appearance: White powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

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Chitosan Powder Usage and Synthesis.

Chitosan has a wide range of antibacterial effect, but different concentrations of chitosan its antibacterial ability is not the same, such as chitosan concentration of 0.1%, within 8d can make the reproduction of a variety of molds in the genus Fusarium completely inhibited, but the concentration of the genus Rhizopus, Penicillium, Aspergillus and other molds do not have the effect.

At a concentration of 0.4%, it had a strong inhibitory effect on Escherichia coli, Proteus vulgaris, Bacillus subtilis and Staphylococcus aureus.

In addition, the antimicrobial properties of chitosan with different degrees of deacylation are different, and the high degree of deacylation of chitosan has strong antimicrobial power. of chitosan has strong antimycobacterial power. One of the reasons is that chitosan interacts with the surface layer of mold cells to increase cell permeability. Chitosan and sodium acetate, adipic acid formulated preservatives antimicrobial effect is more obvious, and does not affect the flavor of food.

Chitosan's antibacterial effect mainly has the following two mechanisms: one is chitosan by adsorption on the cell surface, the formation of a layer of polymer membrane, preventing the transportation of nutrients to the cell, thus playing a bacteriostatic role; another mechanism is chitosan through the infiltration into the cell body, adsorption of anions with anionic cytoplasm within the cell body and flocculation occurs, disrupting normal physiological activities of the cell, thus killing bacteria. The mechanism of chitosan is that chitosan adsorbs the anionic cytoplasm of the cell and flocculation occurs, disrupting the normal physiological activity of the cell, thus killing the bacteria.

Because the cell wall structure of Gram-positive bacteria and Gram-negative bacteria is different, the two effects have different degrees of influence on them, so different relative molecular mass of chitosan, its antibacterial mechanism is different.

Primary Grades and Applications.

• Pharmaceutical-grade chitosan powder is highly favored in drug delivery systems, wound healing products, and medical applications due to its high purity and biocompatibility. Particularly in cancer treatment, folate-modified chitosan nanoparticles enable targeted drug delivery, enhancing therapeutic efficacy.
• Food-grade products are primarily used for food preservation and functional food development, where their antimicrobial and antioxidant properties extend shelf life. Food-grade chitosan powder is also widely incorporated into dietary supplements; studies indicate that a daily dose of 1500 mg benefits blood sugar control in prediabetic individuals.
• Agricultural-grade chitosan powder serves primarily as a natural pesticide and growth promoter. The European Food Safety Authority has approved its use for plant protection by 2025.
• Industrial-grade products play a vital role in water treatment, effectively removing heavy metals and organic pollutants.

Physiological effect of Bulk Chitosan Powder.

Chitosan is a kind of dietary fiber, which has the effect of lowering serum cholesterol, regulating intestinal flora and lowering blood pressure. After the human body ingests chitosan, fecal analysis shows that it is hardly digested and absorbed, so it belongs to a kind of dietary fiber.

Research shows that chitosan has some of the characteristics of dietary fiber, such as water retention, expansion, adsorption and difficult to digest and absorb, etc., can promote peristalsis in the digestive tract, adsorption of toxic substances, increase the volume of defecation, reduce the abdominal pressure and intraintestinal pressure, improve constipation, prevention of colorectal cancer and so on.

Chitosan and gastric mucin have similar physicochemical effects, with inhibition of gastric acid, anti-gastric ulcers, anti-inflammatory effects, it is an anti-gastric acid polysaccharides, swelling and development of viscous plasma in contact with water and adhesion, in the stomach can form a protective film, in order to reduce the stimulation of gastric acid on the ulcer surface.

Food safety: When the dose of chitosan fed to animals reaches 20% of the feed, there are reports of animal deaths. It is analyzed that this is due to the high concentration of chitosan in the animal viscera to form a gel, inhibiting the animal's nutrient absorption.

At present, it is necessary to systematically study the physiological role of chitosan high-viscosity macromolecules and low-viscosity macromolecules, and it is also necessary to make further long-term chronic tests on the safety, toxicology and metabolism of chitosan from a clear source.

Product Methods of Chitosan.

20g of chitin was added to 300mL of 50% NaOH solution, completely infiltrated and then heated and held at 95°C for 1.5h, filtered off the alkaline solution, washed with water to neutrality, and dried at low temperature to obtain 15.6g of colorless and transparent flaky product.

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