Methylcobalamin Raw Materials CAS:11032-49-8

CAS:13422-55-4

MF:C63H90CoN13O14P

MW:1343.4

EINECS:236-535-3

Specification​: 99% min Methylcobalamin powder

Sample:Methylcobalamin powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Dark Red

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Methylcobalamin injection also has the ability to inhibit the abnormal excitation conduction of nerve tissue, promote the maturation and division of orthoerythrocytes, and improve anemia. Mecobalamin can rapidly restore the red blood cell count, hemoglobin, hematocrit value of rats, which are reduced due to B12 deficiency. It is applied to megaloblastic anemia and peripheral nerve disorder caused by vitamin B12 deficiency.

Uses of Methylcobalamin.

Methylcobalamin is an endogenous coenzyme B12 that participates in the one-carbon unit cycle and plays an important role in the transmethylation reaction for the synthesis of methionine from homocysteine.

Used in the treatment of neurological disorders, relief of pain and numbness, quick relief of neuralgia, improvement of pain caused by cervical spondylosis, treatment of sudden deafness, etc.

Pharmacological effect of Methylcobalamin.

Methylcobalamin is a vitamin B12 derivative, named by its chemical structure, it should be called "methyl vitamin B12", and its methylated functional group can participate in the methyl transfer activity in the biochemical process of the body, and it has a promotional effect on the metabolism of nucleic acids, proteins and fats of the neural tissues, and it can stimulate the synthesis of lecithin in the cells of the Schwann's cells to repair the damage. It can stimulate the synthesis of lecithin in Shewan's cells, repair the damage of myelin sheath, and improve the speed of nerve conduction; it can directly enter the nerve cells and stimulate the regeneration of the damaged area of axon; it can stimulate the protein synthesis of nerve cells, strengthen the anabolic metabolism of axon, and prevent the degeneration of axon; and it can participate in the synthesis of nucleic acid, and promote hematopoiesis.

Clinically, it is often used in the treatment of diabetic neuropathy, and long-term use of diabetes mellitus macrovascular complications also has certain efficacy.

Mecobalamin is mainly used for peripheral neuropathy caused by diabetes mellitus and megaloblastic anemia caused by vitamin B12 deficiency, which is widely used in clinic with few side effects.

Product Method of Bulk Methylcobalamin Powder.