High-Purity D-Glucosamine HCl Powder | Joint Health API

CAS: 66-84-2

MF: C6H14ClNO5

MW: 215.63

EINECS: 200-638-1

Specification​: 99% min D-glucosamine Hydrochloride powder

Sample: D-glucosamine Hydrochloride powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1kg

Appearance:  White powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

What is D-glucosamine hydrochloride powder?

D-glucosamine hydrochloride is a naturally occurring amino sugar in the human body, particularly abundant in articular cartilage and synovial fluid. Unlike the commonly available glucosamine sulfate, the hydrochloric acid form provides a higher concentration of pure glucosamine and is free of sodium or potassium salts, making it suitable for individuals who need to restrict electrolyte intake.

This powder supplement is typically extracted from the shells of crustaceans such as shrimp, crab, and lobster, and processed using advanced hydrolysis techniques to create an easily soluble fine powder with high bioavailability, facilitating absorption and utilization by the body.

D-glucosamine Hydrochloride powder Usage and Synthesis.

Aminoglucose hydrochloride can be used to treat osteoarthritis, bursitis, synovitis and frozen shoulder. It can be used for the treatment and prevention of osteoarthritis in all parts of the body, including the knee, hip, spine, shoulder, hand and wrist, and ankle.

Uses and functions of D-glucosamine Hydrochloride powder.

Glucosamine hydrochloride can be made into drugs for the treatment of rheumatoid arthritis, ulcers, enteritis, a nutritional additive for food and cosmetics, and a culture agent for biochemical cells.

Glucosamine hydrochloride is extracted from natural crustacean, which is a kind of marine biological preparation, can promote the synthesis of human mucopolysaccharide, improve the viscosity of synovial fluid, can improve the metabolism of articular cartilage; it has the effect of promoting the effectiveness of antibiotic injection, and is used for the synthesis of the water-soluble anticancer drug chlorourethromycin, which has the anticarcinogenic properties of nitrosoureas, and at the same time, has the characteristics of less toxicity of inhibiting bone marrow, and shows a certain degree of effectiveness in the treatment of Melanoma, lung cancer, kidney cancer, etc. It shows certain efficacy; Supplementation of glucosamine medium can enhance the N-glycosylation of secretory proteins.

Who should consider using D-glucosamine hydrochloride powder?

• Sports enthusiasts and athletes: Runners, weightlifters, tennis players, and others whose joints bear significant stress.
• Office workers: Those who maintain the same posture for long periods, especially those with shoulder, neck, and wrist joints who need extra support.
• Middle-aged and elderly people: As we age, the natural production of glucosamine decreases.
• Those with mild joint discomfort: Those who wish to take proactive measures to maintain joint function.
• Health-conscious individuals focused on prevention: Especially those with a family history of joint problems.

Pharmacological effect of D-glucosamine Hydrochloride powder.

Joint pain caused by wear and tear and degeneration of osteoarticular cartilage is partly due to abnormal synthesis of articular cartilage proteoglycans. Glucosamine is a natural amino monosaccharide that can stimulate chondrocytes to produce proteoglycans with a normal multimeric structure, inhibit cartilage-damaging enzymes such as collagenase and phosphodiesterase A2, and prevent the production of cell-damaging superoxide radicals, thus delaying the onset of osteoarthritic pain.

Integrate D-glucosamine into a healthy lifestyle:

• Combine with moderate exercise: Low-impact activities such as swimming, cycling, and yoga help maintain joint flexibility.
• Maintain a healthy weight: Reduce the burden on joints, especially weight-bearing joints such as the knees and hips.
• Balanced nutrition: Ensure your diet is rich in vitamins C and D, Omega-3 fatty acids, and antioxidants.
• Adequate rest and recovery: Give your joints sufficient time to recover, especially after high-intensity activity.

Frequently Asked Questions

Q1: What is the difference between D-glucosamine hydrochloride powder and glucosamine sulfate?

A: The main difference lies in the binding molecule. The hydrochloride form provides a higher concentration of pure glucosamine (typically 83% compared to 65% of the sulfate) and does not contain additional sodium or potassium ions. Some studies have found that both have similar effects, but the hydrochloride form may be more suitable for people who need to restrict their electrolyte intake.

Q2: How long does it take to see results?

A: Joint health supplements typically take a long time to show results. Most users report starting to feel improvement after 4-8 weeks of continuous use. Cartilage repair is a slow process, and it is recommended to continue use for at least 3 months to fully evaluate the effects.

Q3: Is D-glucosamine hydrochloride powder safe?

A: It is safe for most people when used at the recommended dosage. Common side effects (occurring in approximately 10-15%) may include mild indigestion, drowsiness, or headache. It is recommended to take it with meals to reduce stomach upset. People with shellfish allergies should choose products from non-seafood sources.

Q4: Can it be taken with other supplements such as chondroitin or MSM?

A: Yes. In fact, many joint health formulas combine glucosamine, chondroitin, and MSM (methylsulfonylmethane). Studies have shown that these ingredients may have a synergistic effect, working together to support joint comfort and flexibility.

Q5: Can people with diabetes use D-glucosamine?

A: Although glucosamine is chemically an amino sugar, studies have shown that it does not significantly affect blood sugar levels or insulin sensitivity. However, people with diabetes should still consult a healthcare provider before starting any new supplement and monitor their blood sugar regularly.

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