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Raw Materials N-acetyl Cysteine powder
Product Overview:
N-Acetyl-L-Cysteine is acidic in aqueous solution (pH 2-2.75 in 10g/L H2O), mp 101-107°C. It is the N-acetylated derivative of cysteine, containing sulfhydryl group in the molecule, which can break the disulfide bond (-S-S-) of the peptide bond of mucin, thus turning the mucin chain into a small molecule peptide chain, and lowering the viscosity of the mucin, so it is a dissolving agent for mucous phlegm, purulent phlegm, and respiratory tract mucus.
Raw Materials N-acetyl Cysteine powder Attributes
CAS:616-91-1
MF:C5H9NO3S
MW:163.19
EINECS:210-498-3
Specification: 99% min N-acetyl Cysteine powder
Sample:N-acetyl Cysteine powder
Packaging:1kg/bag, 25kg/drum
Brand: Raw Materials
Appearance:White
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Raw Materials N-acetyl Cysteine powder Details
N-acetyl Cysteine Powder Usage and Synthesis.
Used as a mucous phlegm dissolving drug. Suitable for respiratory obstruction caused by large amounts of mucous phlegm. It is also used for the detoxification of acetaminophen poisoning. Because of the special odour of this product, it is easy to cause nausea and vomiting.
It has an irritating effect on the respiratory tract and can cause bronchospasm, generally used in combination with isoproterenol and other bronchodilators, and at the same time with sputum suction to expel sputum. It is not suitable for contact with metals (e.g. Fe, Cu), rubber and oxidising agents.
Should not be used in conjunction with antibiotic drugs such as penicillin, cephalosporin, tetracycline, etc., so as not to reduce its antibacterial effect. Use with caution in bronchial asthma.
Uses of N-acetyl Cysteine.
N-Acetyl-L-Cysteine is a biochemical reagent, medicine, the product is used as an expectorant, called phlegm easy to clean, easy to cough quiet. It has a disintegrating effect on viscous phlegm.
The mechanism of action is that the sulfhydryl group contained in the molecular structure of the product can break the disulfide bond in the polypeptide chain of mucin in mucous phlegm, so that the mucin is decomposed, lowering the viscosity of phlegm and making it liquefied and easy to cough out.
It is suitable for people with acute and chronic respiratory diseases whose sputum is thick and not easy to cough out, as well as those who have a large amount of mucous sputum obstruction and cause critical symptoms due to difficult suction and aspiration.
Drug interactions of N-acetyl Cysteine.
1.N-acetyl-L-cysteine should not be mixed with penicillin, cephalosporin and tetracycline antibiotics, as it can make the latter ineffective.
2. Combining or alternating with isopropyl epinephrine can improve the efficacy and reduce the adverse reactions.
3. Avoid contact with metal and rubber utensils, oxidising agents and oxygen.
Product Method of Bulk N-acetyl Cysteine Powder.
L-cysteine and acetic anhydride were used as raw materials, the crude product was obtained by acylation reaction, and the finished product of N-acetyl-L-cysteine was refined by activated carbon and ether.
