HRK Supply Cyproheptadine hydrochloride hcl Powder

CYPROHEPTADINE HYDROCHLORIDE Raw Materials Powder

CAS: 969-33-5

MF: C21H22ClN

MW: 323.86

EINECS: 213-535-1

Specification: 99% min Cyproheptadine hydrochloride Powder

Sample: Cyproheptadine hydrochloride Powder Avaliable

Packaging:1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1kg

Appearance: white powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Last updated: April 2026

What is Cyproheptadine Hydrochloride Powder?

Cyproheptadine Hydrochloride (CAS No. 129-03-3 / 41354-29-4) is a first-generation antihistamine with additional anticholinergic and antiserotonergic properties. In its pure powder form, it is a white to slightly yellowish crystalline substance, widely used as a raw material in the production of tablets, syrups, and specialized health formulas.

How It Works: The Science of Appetite Stimulation

Unlike standard supplements, Cyproheptadine works by antagonizing serotonin receptors in the hypothalamus—the brain's "appetite center." By modulating these signals, it effectively:

1. Triggers Hunger: Increases the desire to consume food.

2. Growth Support: Often used in pediatric and geriatric care to combat "failure to thrive."

3. Allergy Relief: Blocks H1 receptors to alleviate symptoms like hay fever and urticaria.

Cyproheptadine hydrochloride Powder Usage and Synthesis.

Clinically, cyproheptadine hydrochloride is mainly used for acute and chronic urticaria (especially cold urticaria has a good effect), papular urticaria, vascular edema, allergic eczema, contact dermatitis, food allergy, drug allergy, allergic rhinitis, hay fever, allergic conjunctivitis, insect sting allergy and migraine. It has certain therapeutic effect on bronchial asthma. Can also be used for Cushing syndrome, acromegaly adjuvant treatment. It can also be used as an appetite enhancer for nervous fear of food. There are reports of treating acanthosis nigricans and preventing necrotizing pyoderma.

Key Benefits & Applications

• Appetite Stimulant: Proven effective for individuals with anorexia or chronic illness-related weight loss.

• Antihistamine Action: Relieves itchy eyes, sneezing, and runny nose.

• Serotonin Syndrome Management: Used in clinical settings to treat serotonin toxicity.

• Post-Gastrectomy Dumping Syndrome: Helps manage symptoms after certain stomach surgeries.

FAQs: 

In the United States, Cyproheptadine is an FDA-approved prescription medication. It cannot be legally sold as a "dietary supplement." It must be marketed as an API for compounding or pharmaceutical manufacturing.

Yes, it is clinically used for weight gain, but dosage must be strictly monitored to avoid side effects like extreme drowsiness or dry mouth.

Keep it in a cool, dry place (20℃ to 25℃), away from direct sunlight, in a tightly sealed container to maintain its potency.

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