High Purity Sodium Hyaluronate HA Powder Manufacturer

CAS:9067-32-7

MF:C14H22NNaO11

MW:403.31

EINECS:618-620-0

Specification​: 99% min Sodium Hyaluronate Powder

Sample: Sodium Hyaluronate Powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Henrikang

MOQ: 1 kg

Appearance: white powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

What is Sodium Hyaluronate Powder?

Sodium hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring substance in the human body, particularly abundant in the skin, eyes, and synovial fluid. Compared to hyaluronic acid, sodium hyaluronate has smaller molecules, higher stability, and is more easily absorbed and utilized by the body.

Key Characteristics:

• Superior Water Retention Capacity: Can hold 1000 times its own weight in water.
• Excellent Biocompatibility: Highly compatible with human tissues.
• Superior Permeability: Small molecular structure facilitates skin penetration.

Sodium Hyaluronate Powder Usage and Synthesis.

Sodium hyaluronate is a component of normal aqueous humor and vitreous body. When injected into the anterior chamber or vitreous cavity, the normal concentration of these parts can be temporarily increased. The Healon in the anterior chamber was gradually diluted by the new aqueous humor and discharged through the Angle of the chamber via the scleral venous sinus. The Healon injected into the vitreous cavity gradually permeates into the anterior chamber and is diluted with aqueous humor. In monkey eye experiments, it was observed that the Healon injected into the vitreous cavity disappeared completely after 60 to 70 days. In this process, the concentration decreases while the molecular size remains the same. The injection of Healon into the anterior chamber of the monkey disappeared within 1 week, similar to the clinical observation of the human eye.

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Uses of Sodium Hyaluronate.

① Can protect corneal endothelium, epithelium, iris and retina during operation.

② Replace aqueous humor without loss, so the anterior chamber depth can be maintained during surgery.

③ Injection into the vitreous cavity can help the retinal reset due to pressure.

④ In glaucoma surgery can enter the conjunctival filter pillow to maintain the filter pillow bulge.

⑤ Helps to separate the tissue surface to reduce adhesion.

It is widely used in the high-end cosmetics industry for dry eye syndrome

Pharmacological action of Sodium Hyaluronate.

Sodium hyaluronate can promote wound healing. Sodium hyaluronate can form a large molecular mesh barrier on the surface of the eye tissue, prevent the inflammatory substances from entering the wound and lesion area, and significantly improve the viscosity and adhesion of the drug solution, so that the drug can be concentrated on the surface of the cornea for a long time, to achieve a long-term and powerful effect. Sodium hyaluronate can stabilize tear film, prolong tear film rupture time, and relieve dry eye symptoms. For keratitis, corneal ulcer, corneal injury or other chemical and physical factors caused by corneal burns.

How to Properly Use Sodium Hyaluronate Powder

Oral Supplementation

• Dosage Recommendation: Generally recommended 50-200 mg daily, adjustable according to individual needs.
• Usage: Dissolve the powder in water, juice, or smoothie.
• Optimal Time: Recommended to take on an empty stomach or with meals to improve absorption.

Topical Application Guidelines

• DIY Skincare Recipes: Add a small amount of powder to unscented creams, serums, or masks.
• Concentration Recommendation: 0.1%-1% concentration is suitable for most skincare products.
• Precautions: A patch test is recommended before first use.

Synergistic Effects with Other Supplements

• Combined with Vitamin C: Enhances collagen synthesis.
• Combined with collagen: Provides comprehensive support for skin health.
• Combined with glucosamine and chondroitin: Synergistically supports joint function.

Product Method of Bulk Sodium Hyaluronate Powder.

It is a salt of the carboxyl group of hyaluronic acid and sodium metal ions. Hyaluronic acid is commonly found in animals and humans, such as skin, muscle, cartilage, brain, comb, artery and vein walls. Commonly used raw materials are male crown, umbilical cord, ox eye and so on. The preparation method of chicken comb as raw material is as follows.

1. Extraction: Fresh comb washed with acetone, dehydrated and crushed, soaked in distilled water for 24h, repeated 3 times, combined with filtrate.

2. Remove protein and precipitation: the extraction solution is mixed and stirred with equal volume chloroform for 3h, the aqueous phase is separated, 2 times the amount of ethanol is added, the precipitation is collected, the acetone is dehydrated, and the vacuum drying is done to obtain the crude hyaluronic acid.

3. Hyaluronic acid is obtained by enzymolysis, complexation, dissociation and precipitation. And then it forms a salt with the metal sodium ion.

Frequently Asked Questions

Q1: What is the difference between sodium hyaluronate powder and hyaluronic acid?

A: Sodium hyaluronate is the sodium salt of hyaluronic acid. It has smaller molecules, higher stability, and is more easily absorbed by the skin, while maintaining the same moisturizing properties.

Q2: Is sodium hyaluronate powder really effective for joint health?

A: Multiple clinical studies support the benefits of sodium hyaluronate for joint health. An 8-week study showed that participants who supplemented with 80 mg of sodium hyaluronate daily experienced a 40% improvement in joint comfort.

Q3: How can I tell if I have purchased high-quality sodium hyaluronate powder?

A: Look for products with clear purity markings (usually >95%), third-party laboratory test reports, cGMP certification, and clearly stated molecular weight information. Well-known brands in Europe and America usually provide this information.

Q4: Can sodium hyaluronate powder be used both topically and orally at the same time?

A: Yes, many users use a combination of internal and external methods. Oral administration supports overall body hydration and joint health, while topical application provides enhanced hydration for specific skin areas.

Q5: How long does it take to see results?

A: This depends on the purpose of use and individual constitution. For skin hydration, some users can feel the difference within a few days; for joint support, it usually takes 2-4 weeks of continuous use to see a noticeable difference.

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