Berberine Raw Material Berberine Powder

CAS: 2086-83-1

MF: C20H18NO4

MW: 336.37

EINECS: 218-229-1

Specification​: 99% min Berberine 

Packaging: 1kg/bag. 25kg/bag

Brand: Henrikang

Appearance: Yellow Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

China Berberine Raw Material Factory Supply Berberine Nutritional SupplemenBerberine Powder Raw Material, High Quality Berberine Powder Purity 98% is also known as berberine, is the main effective component extracted from the rhizome of Coptis coptis in Ranunculaceae. It mostly exists in nature in the form of quaternary ammonium salt.

Manufactory Supply Berberine Powder Raw Material, High Purity Berberine Powder Nutritional Supplement Berberine Raw Powder, High Quality Berberine Raw Powder.

Uses and functions of Berberine Powder

Berberine, also known as berberine, is the main effective component extracted from the rhizome of Coptis coptis in ranunculaceae. It mostly exists in the form of quaternary ammonium salt in nature, and its hydrochloride is commonly used in clinical practice. Berberine hydrochloride has a variety of pharmacological effects such as antimicrobial, antiarrhythmic, lipid-lowering, glucose-lowering, anti-inflammatory, anti-tumor, sedative and hypnotic.

Bioactive pharmacological effects of Berberine Raw Powder

Rhizoma coptidis is a famous traditional Chinese medicine. It is listed as the top quality in Shennong Bencao Jing (Shennong's Classic of Materia Medica). It is cold in nature and bitter in taste.

Among them, berberine (berberine) has the most content and is one of the most effective components. It has good therapeutic and health effects on the cardiovascular system, nervous system and digestive system, and is a commonly used Chinese herbal medicine.

In recent years, some new uses have been found, such as the treatment of essential hypertension, arrhythmia, hyperlipidemia, peptic ulcer, type II diabetes, etc., which can be said to be the new use of old drugs.

In addition, modern pharmacological studies have confirmed that berberine has significant effects of anti-heart failure, anti-arrhythmia, lowering cholesterol, anti-vascular smooth muscle proliferation, improving insulin resistance, anti-platelet, anti-inflammatory, and so on. Therefore, berberine may have a broad and important application prospect in cardiovascular system and nervous system diseases.

Production method of Berberine Powder

Isosafrole was isomerised under reduced pressure to isosafrole, which was oxidised to produce piperonal.

Piperonyl aldehyde and nitromethane condensation to β-nitro-3,4-dioxomethylidene styrene, further reduction of piperonyl ethylamine [1484-85-1]: piperonyl ethylamine and o-veratraldehyde condensation, and then catalytic hydrogenation, salting, cycling, alkalisation to berberine. Continue to salt with hydrochloric acid to get berberine.

1.Condensation, catalytic hydrogenation, salt will be anhydrous ethanol and o-veratraldehyde mixed, under the stirring and then add piperonyl ethylamine, slightly heated to make all dissolved.