Food Additives API Natamycin Raw Powder

CAS:7681-93-8

MF: C33H47NO13

MW:665.73

EINECS:231-683-5

Specification​: 99% min Natamycin Powder

Sample:Natamycin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Natamycin Powder Usage and Synthesis.

Natamycin has a strong inhibitory ability to moulds, yeasts and fungi, but it has no inhibitory effect on other microorganisms such as bacteria and viruses.

Natamycin has a certain resistance to heat treatment, relatively stable in the dry state, can withstand a short period of high temperature (100 ℃); but because it has a cyclic chemical structure, more sensitive to ultraviolet rays, so it is not suitable for contact with sunlight.

Anchor stability of Natamycin activity is affected by PH value, temperature, light intensity and oxidants and heavy metals, so the product should avoid contact with oxides and sulfur-hydrogen compounds, etc.

Uses and functions of Natamycin.

Anti-mould agent. Good anti-mould effect when used on air-exposed food surfaces where moulds tend to proliferate. Used in fermented cheese can selectively inhibit the reproduction of moulds and allow normal growth and metabolism of bacteria. The product should be stored under well sealed, no direct sunlight, <15℃.

An antifungal polyene antibiotic that inhibits fungal growth by specifically binding to ergosterol. Unlike mycobacteria and phlebotinum, natamycin does not alter the permeability of cell membranes.

Producing an Effect of Natamycin.

Nathamycin is a "polyene macrolide" fungal inhibitor produced by the fermentation of Streptomyces natalis, and is currently the only internationally approved antifungal biofood preservative with high efficiency, broad-spectrum, safety and natural properties.

Natamycin relies on its lactone ring structure to interact with sterols on fungal cell membranes to form sterol compounds, thereby destroying the structure of the cytoplasmic membrane.

The hydrophilic portion of the macrolide forms water pores in the membrane, impairing cell membrane permeability, which in turn causes the exudation of amino acids, electrolytes, and other substances from the fungus, and the death of the fungus.

Because, as a polyene antibiotic natamycin mechanism of action is to bind the sterols on the fungal cell membrane. The cell surface of animal organism lacks sterol, and it is not sensitive to polyene antibiotics.

Therefore, natamycin is harmless to human body, and it is difficult to be absorbed by human digestive tract.

No mutagenic, carcinogenic and sensitising effects. It is a natural antifungal agent, possessing the characteristics of safety, high efficiency, natural and health.

Production Method of Bulk Natamycin Powder.

Produced by controlled fermentation of Streptomyces natalensis (Streptomyces natalensis)