Tetracycline Hcl raw material Tetracycline Hcl Powder

CAS:64-75-5

MF: C22H25ClN2O8

MW:480.9

EINECS:200-593-8

Specification​: 99% min Tetracycline Hcl Powder

Sample:Tetracycline Hcl Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: faint yellow to yellow

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Tetracycline Hcl Powder Usage and Synthesis.

Tetracycline hydrochloride is a broad-spectrum antibiotic with bactericidal effect at high concentration. In addition to common Gram-positive, Gram-negative and anaerobic bacteria, most of the genera of Rickettsiae, Mycoplasma, Chlamydia, atypical Mycobacteria, Spirochetes, Actinobacillus, Bacillus anthracis, Listeria monocytogenes, Clostridium perfringens, Nucella spp. are susceptible to this product.

Tetracycline hydrochloride acts better on gram-positive than gram-negative bacteria, but Enterococcus spp. and penicillin-resistant gonococci are resistant to it.

Tetracycline hydrochloride has good antibacterial effect on gram-negative bacteria such as Vibrio, Brucella, Campylobacter, Yersinia, etc. It has no antibacterial activity against Pseudomonas aeruginosa.

Uses and functions of Tetracycline Hcl.

Tetracycline hydrochloride is an antibiotic used for the treatment of non-bacterial infections such as chlamydial infections, rickettsial diseases, mycoplasma pneumonia, regression fever, etc. It is also used for the treatment of brucellosis, cholera, rabbit fever, rat-bite fever, anthrax, tetanus, bubonic plague, actinomycosis, gas gangrene, and respiratory, biliary, and urinary tract infections caused by sensitive bacteria, as well as soft-tissue skin infections.

Characteristic of Tetracycline Hcl.

Tetracycline hydrochloride is a yellow crystal, odourless. Bitter taste. Easy to absorb moisture. When exposed to light, the colour becomes darker. Soluble in water, in methanol. Ethanol, insoluble in ether, hydroxyl.

It is an antimicrobial substance isolated from the culture fluid of Actinobacillus goldenseal streptococcus, which has good inhibitory effect on Gram-positive bacteria, negative bacteria, rickettsiae, filtration line viruses, spirochetes, and even protozoa, and is ineffective against tuberculosis, aspergillus, and so on.

Drug interactions of Bulk Tetracycline Hcl Powder.

1, this product can inhibit the activity of plasma prothrombinogen, so patients receiving anticoagulation therapy need to adjust the dose of anticoagulants.

2、Drugs containing calcium, magnesium, iron and other metal ions can form insoluble complexes with this product, so that the absorption of this product is reduced.

3、Combined with the general anaesthetic drug methoxyflurane, it can enhance its nephrotoxicity.

4, with strong diuretic drugs such as furosemide and other drugs can aggravate renal impairment.

5, with other hepatotoxic drugs (such as anti-tumour chemotherapy drugs) can aggravate liver damage.

6, lipid-lowering drugs Kaolai enamine or Kaolai Tipo can affect the absorption of this product, must be taken separately at intervals of several hours.

7, this product can reduce the effect of contraceptive pills, increase the possibility of bleeding outside the menstrual period.

8, and acid-making drugs such as sodium bicarbonate when used together, due to the increase in pH value in the stomach, can make the absorption of this product to reduce the activity of the reduction, so should not be taken within 1-3 hours after taking this product to take acid-making drugs.