Isonicotinic Acid Raw Material Powder

CAS: 55-22-1

MF: C6H5NO2

Specification​: 99% min Isonicotinic Acid

Sample:  Isonicotinic Acid Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Isonicotinic Acid Powder Usage and Synthesis:

Isonicotinic Acid Raw Material is a widely used intermediate, mainly used as the raw material of first-line anti-tuberculosis drugs such as isoniazid (Ramifen), terfenadine and isonicotinate. Isonicotinic Acid Powder can also be used as anti-corrosion agent, Electroplating additives, photosensitive resin stabilizers, polyvinyl chloride heat stabilizers and non-ferrous metal flotation agents, etc. Isonicotinic acid is also known as pyridine-4-carboxylic acid. White needle crystal. Isonicotinic acid can be used as a pharmaceutical intermediate. There are many methods for synthesizing isonicotinic acid, mainly divided into oxidation, hydrolysis and biocatalysis. Odorless and sublimable. Molecular weight 123.11. The melting point is 319°C. Slightly soluble in cold water, soluble in hot water, insoluble in alcohol, benzene, ether. It is an amphoteric compound, soluble in both acid and alkali. Soluble in hot water and ethanol, slightly soluble in cold water and ether. Stable to heat and oxidation.

Pharmacokinetics of Isonicotinic Acid Powder:

Isonicotinic acid is a widely used intermediate. It is mainly used as the raw material of first-line anti-tuberculosis drugs such as isoniazid (remifen), terfenadine and isonicotinate. It can also be used as an anti-corrosion agent, electroplating additive, photosensitive Resin stabilizer, PVC heat stabilizer and non-ferrous metal flotation agent, etc. Isoniazid can be obtained by condensing isonicotinic acid with hydrazine hydrate and melting and dehydrating. Isoniazid has a good antibacterial effect on Mycobacterium tuberculosis, with good curative effect, small dosage and relatively low toxicity. It is used for the treatment of various types of pulmonary tuberculosis It can also be used for tuberculous meningitis and other extrapulmonary tuberculosis in advanced stage, dissolution dissemination stage, and absorption improvement stage. The preparations include tablets, injections, etc.

Clinical Application of Isonicotinic Acid Powder:

Isonicotinic acid, English name: isonicotinic acid, CAS number: 55-22-1, molecular formula: C6H5NO2, molecular weight: 123.102. It is mainly used in the preparation of isoniazid, an anti-tuberculosis drug, and also used in the synthesis of derivatives such as amides, hydrazides, and esters. Isonicotinic Acid Powder is used as a pharmaceutical intermediate, mainly for the preparation of isoniazid, an anti-tuberculosis drug. Isonicotinic Acid Powder is used for the synthesis of derivatives such as amides, hydrazides, and esters. Isonicotinic acid, also known as 4-carboxypyridine, is a plant It is the intermediate of the growth regulator anti-trivalamine, and also the intermediate of isoniazid for anti-tuberculosis medicine. Packed in a clean iron drum and stored in a cool, ventilated place. Store and transport according to general chemical regulations. Using 4-picoline as raw material, it can be prepared by continuous oxidation with vanadium pentoxide as catalyst. The purity of the industrial product isonicotinic acid is more than 95%, and the yield of the above method is 70-75%. Each ton of product consumes 1070kg of 4-picoline. Used as a pharmaceutical intermediate, mainly used in the preparation of anti-tuberculosis drug isoniazid, and also used in the synthesis of amides, hydrazides, esters and other derivatives.