Oleanolic Acid Raw Materials Oleanolic Acid Powder

CAS:508-02-1

MF:C30H48O3

MW:456.7

EINECS:208-081-6

Specification: 99% min Oleanolic Acid Powder

Sample:Oleanolic Acid Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Light Yellow

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Oleanolic Acid Powder Physiological effect.

1, oleanolic acid has anti-inflammatory, sedative, cardiotonic, diuretic, hypolipidemic,hypoglycemic as well as hepatoprotective and enzyme-lowering, enhancement of immunity and inhibition of the growth of S180 tumour strains and other roles, it is the development of the treatment of liver disease and hypoglycemic and other effective components of the drug.

2, oleanolic acid has a protective effect on chromosome damage, and has a preventive effect on experimental atherosclerosis. Clinically used in the treatment of infectious acute jaundice hepatitis, chronic viral hepatitis, with a significant reduction of ghrelin and yellowing effect.

3, oleanolic acid has the effect of inhibiting hepatic fibroplasia, by oleanolic acid treatment of hepatic fibrosis in rats, hepatic fibroplasia is serious and obviously reduce the hepatic collagen content, suggesting that it has the effect of preventing and controlling cirrhosis of the liver.

4, reduce the cirrhotic rat brain homogenate kojic acid level: due to the brain homogenate kojic acid level decreased significantly, can inhibit the generation of pseudo-neurotransmitter, so it is conducive to the prevention and treatment of hepatic encephalopathy.

5, oleanolic acid capsule for liver disease auxiliary drugs class of non-prescription drugs, for acute and chronic hepatitis adjuvant therapy. It has a certain protective effect on liver injury, can make the elevated serum alanine aminotransferase decrease, promote liver cell regeneration, accelerate the repair of necrotic tissue.

Uses and Function of Oleanolic Acid.

A triterpenoid isolated from medicinal plants. Antitumour and hepatoprotective agent. Used as a reference compound in the quantification by high performance thin layer chromatography

(HPTLC) in the roots of Tinctoria spp.

Oleanolic acid is a naturally occurring triterpenoid widely found in food and medicinal plants.It is used as an adjuvant in liver diseases, for all types of hepatitis, with the ability to promote liver cell regeneration and accelerate the repair of damaged liver cells, as well as cardiotonic,diuretic and anti-inflammatory effects.

Physicochemical property of Oleanolic Acid.

Oleanolic acid is widely present in plants, with a general content of 0.2% to 2%. Cucurbitaceae plant Luo pot bottom content is higher for 1.5% to 2%, chasteberry fruit content of 0.6% to 0.7%. Oleanolic acid is white needle crystal (ethanol), odourless, tasteless. Unstable to acid and alkali.

Melting point 308 ~ 310 ° C, [α] 20D + 73.3 ° (c = 0.15, chloroform), insoluble in water, soluble in methanol, ethanol, ether, acetone and chloroform.

Production process of  Bulk Oleanolic Acid Powder.