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Pimaricin Raw Materials Pimaricin Powder
Product Overview:
Nathamycin, also known as pimaricin and swimmermycin, was firstly isolated from Streptomyces natalis in 1955, and its activity is much better than sorbic acid.In June 1982, FDA formally approved that nathamycin can be used as food preservative, and also categorized it as one of the GRAS products. Nathamycin is a highly effective inhibitor of molds, yeasts and fungi, used to inhibit molds, yeasts and fungi in food, it is very safe and reliable for human body and does not affect the flavor of the product, it is widely used in the world for cheese, meat products, pastries, fruit juices and other foods. The product is refined from Streptomycesnatalensis by deep fermentation and multi-step extraction process, and its preparation is made by mixing 50% natamycin and 50% lactose.
Pimaricin Raw Materials Pimaricin Powder Attributes
CAS:7681-93-8
MF:C33H47NO13
MW:665.73
EINECS:231-683-5
Specification: 99% min Pimaricin Powder
Sample:Pimaricin Powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance:White
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Pimaricin Raw Materials Pimaricin Powder Details
Pimaricin Powder Usage and Synthesis.
Natamycin has strong inhibitory ability to molds, yeasts and fungi, but has no inhibitory effect on other microorganisms such as bacteria and viruses.
Natamycin has a certain resistance to heat treatment, relatively stable in the dry state, can withstand a short period of high temperature (100 ℃); but because it has a cyclic chemical structure, more sensitive to ultraviolet light, so it is not suitable for contact with sunlight.
The anchor stability of Natamycin activity is affected by PH value, temperature, light intensity and oxidizing agents and heavy metals, so the product should avoid contact with oxides and sulfur-hydrogen compounds.
Uses and Function of Pimaricin.
Anti-mold agent. Good anti-mold effect when used on air-exposed food surfaces where molds tend to proliferate. Used in fermented cheese can selectively inhibit the propagation of mold and allow normal growth and metabolism of bacteria. The product should be stored under well sealed, no direct sunlight, <15℃.
An antifungal polyene antibiotic that inhibits fungal growth by specifically binding to ergosterol. Unlike mycobacteria and phlebotinum, natamycin does not alter the permeability of cell membranes.
Nathamycin is a "polyene macrolide" fungal inhibitor produced by the fermentation of Streptomyces natalis, and is currently the only internationally approved antifungal biofood preservative with high efficiency, broad-spectrum, safety and natural properties.
Natamycin relies on its lactone ring structure to interact with sterols on the fungal cell membrane to form sterol compounds, thus destroying the structure of the cytoplasmic membrane. The hydrophilic portion of the macrolide forms water pores in the membrane, impairing cell membrane permeability, which in turn causes the exudation of amino acids, electrolytes and other substances from the fungus, and the death of the fungus. Because, as a polyene antibiotic natamycin mechanism of action is to bind the sterols on the fungal cell membrane.
The cell surface of the animal body lacks sterols, and it is not sensitive to polyene antibiotics. Therefore, natamycin is harmless to human body, and it is difficult to be absorbed by human digestive tract. No mutagenic, carcinogenic and sensitizing effects. It is a natural antifungal agent, possessing the characteristics of safety, high efficiency, natural and health.
Caveat of Pimaricin.
Product Methods of Bulk Pimaricin Powder.
Produced by controlled fermentation of Streptomyces natalensis.
