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  • Nicotinamide Mononucleotide Raw Materials powder

    • Nicotinamide Mononucleotide Raw Materials powder
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    Product Overview:

    Beta-nicotinamide mononucleotide is a product of the extracellular nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It improves glucose tolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression associated with oxidative stress, inflammatory responses, and circadian rhythms, in part through SIRT1 activation.

    Nicotinamide Mononucleotide Raw Materials powder Attributes

    Nicotinamide Mononucleotide Raw Materials powder

    CAS:1094-61-7

    MF:C11H15N2O8P

    Nicotinamide Mononucleotide

    MW:334.22

    EINECS:214-136-5

    Specification​: 99% min Nicotinamide Mononucleotide powder

    Sample:Nicotinamide Mononucleotide powder

    Packaging:1kg/bag, 25kg/drum

    Brand: Raw Materials

    Appearance: White

    Storage: Cool Dry Place

    Shelf Life: 2 Years

    Test Method: HPLC

    Nicotinamide Mononucleotide Raw Materials powder Details

    Nicotinamide Mononucleotide powder Usage and Synthesis.

    Beta-nicotinamide mononucleotide is the precursor substance of NAD+, a cofactor of longevity proteins in the human body.

    NAD+ is an important coenzyme of the tricarboxylic acid cycle, which promotes the metabolism of sugars, fats, and amino acids, and participates in the synthesis of energy; NAD+ is also the only substrate for the coenzyme I depletion enzymes (the only substrate for the DNA repair enzyme PARP, the only substrate for the longevity proteins Sirtuins, and the only substrate for the cyclic ADP-ribose synthetase CD38/157).

    NAD+ is involved in all aspects of human metabolism and is a key coenzyme. Without NAD+, metabolism will not work, and the elderly lack NAD+, so all kinds of big and small problems come, and by supplementing NAD+ additionally, it can be a comprehensive anti-aging.

    Preclinical studies have shown a variety of pharmacological activities of NMN in cardiac and cerebral ischemia, Alzheimer's disease, dietary and age-induced type 2 diabetes and obesity, NMN as a precursor drug for NAD+, mainly synthesized in the body to play a pharmacological role in the synthesis of NAD+, all of which are related to the lack of NAD+.

    Nicotinamide Mononucleotide

    Uses and functions of Nicotinamide Mononucleotide powder.

    In mammals, β-nicotinamide mononucleotide is produced from nicotinamide (Nam) catalyzed by Nampt (a protease in vivo), and subsequently nicotinamide mononucleotide is catalyzed by nicotinamide mononucleotide adenylyltransferase to produce NAD+. Nicotinamide mononucleotides are a direct way to replenish NAD+.

    It is by significantly enhancing the ability to repair intracellular DNA damage that nicotinamide mononucleotide ultimately achieves the reversal of aging. Nicotinamide mononucleotide is converted into nicotinamide adenine dinucleotide (NAD), which is essential for energy metabolism in the body.

    In mouse tests, it has been shown that nicotinamide mononucleotide can activate a gene called acetylase in the body, thus exerting such effects as prolonging life and treating diabetes, etc. NAD is a substance that the human body can originally produce, and studies have confirmed that the amount of NAD in the body decreases with age.

    Nicotinamide Mononucleotide

    Pharmacological effect of Nicotinamide Mononucleotide powder.

    Product Method of Bulk Nicotinamide Mononucleotide powder.

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