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nmn Raw Materials CAS:1094-61-7 β-Nicotinamide Mononucleotide
Product Overview:
β-Nicotinamide mononucleotide is a product of the extracellular nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It improves glucose tolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
nmn Raw Materials CAS:1094-61-7 β-Nicotinamide Mononucleotide Attributes
CAS:1094-61-7
MF:C11H15N2O8P
MW:334.22
EINECS:214-136-5
Specification: 99% min nmn powder
Sample:nmn powder
Packaging:1kg/bag, 25kg/drum
Brand: Raw Materials
Appearance: White
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
nmn Raw Materials CAS:1094-61-7 β-Nicotinamide Mononucleotide Details
nmn Powder Usage and Synthesis.
β-Nicotinamide mononucleotide is the precursor of NAD+, a cofactor of longevity proteins in the human body.
NAD+ is an important coenzyme in the tricarboxylic acid cycle, promoting the metabolism of sugars, fats, and amino acids, and participating in the synthesis of energy; NAD+ is also the only substrate of coenzyme I consuming enzymes (the only substrate of DNA repair enzyme PARP, the only substrate of longevity protein Sirtuins, and the only substrate of cyclic ADP ribose synthetase CD38/157).
NAD+ participates in all aspects of human metabolism and is a key coenzyme. Without NAD+, metabolism will not work. Elderly people lack NAD+, so various major and minor problems arise. By supplementing NAD+, comprehensive anti-aging can be achieved.
Uses of nmn.
In mammals, β-nicotinamide mononucleotide is generated by nicotinamide (Nam) under the catalysis of Nampt (a protease in the body), and then nicotinamide mononucleotide generates NAD+ under the catalysis of nicotinamide mononucleotide adenylyltransferase. Nicotinamide mononucleotide is a direct way to supplement NAD+.
Nicotinamide mononucleotide achieves the effect of reversing aging by significantly improving the ability to repair DNA damage in cells. Nicotinamide mononucleotide will be converted into "nicotinamide adenine dinucleotide (NAD)", which is essential for energy metabolism in the body.
In mouse experiments, it was confirmed that nicotinamide mononucleotide can activate a gene called acetylase in the body, thereby playing a role in prolonging life and treating diabetes. NAD is a substance that the human body can originally produce. Studies have shown that the content of NAD in the body decreases with age.
Preparation method of nmn.
Product Method of Bulk nmn Powder.
