Supply nicotinamide riboside raw Materials Powder

CAS:23111-00-4

MF:C11H15ClN2O5

MW:290.7

EINECS:200-184-4

Specification​: 99% min nicotinamide riboside Powder

Sample:nicotinamide riboside Powder

Packaging:1kg/bag, 25kg/drum

Brand: raw Materials

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

nicotinamide riboside Powder Usage and Synthesis.

The main applications of nicotinamide riboside include increasing tissue NAD concentration, ‌ inducing insulin sensitivity, ‌ enhancing sirtuin function, ‌ improving mitochondrial health, ‌ stimulating mitochondrial function and inducing new mitochondria production, ‌ and possibly having neuroprotective effects. ‌

Nicotinamide nucleoside (‌NR) ‌, as a derivative of vitamin B3, ‌ is not only used in skin care products, ‌, such as anti-yellow, ‌ anti-aging, ‌ antioxidant, ‌ is also an important ingredient in whitening field, ‌ is often added in some cosmetics and skin care products. ‌ In addition to skin care, ‌ nicotinamide riboside has been found to act as a neuroprotective agent and ‌ may be used to treat neurodegenerative diseases such as dementia and ‌ Parkinson's disease. ‌

A Phase I clinical trial found that ‌ oral niacinamide riboside significantly increased levels of niacinamide adenine dinucleotide (‌NAD) ‌ in the brain, ‌ altered brain metabolism, ‌ decreased levels of inflammatory cytokines in serum and cerebrospinal fluid, and ‌ improved clinical symptoms in patients with Parkinson's disease. ‌

Uses of nicotinamide riboside.

Nicotinamide riboside has been implicated in increasing tissue NAD concentration and inducing insulin sensitivity as well as enhancing deacetylase (sirtuin) function. Its ability to increase NAD production suggests that niacinamide riboside can also improve mitochondrial health, stimulate mitochondrial function, and induce the production of new mitochondria. Other studies using nicotinamide riboside in Alzheimer's disease models have shown that the molecule is bioavailable for the brain and may provide neuroprotective effects by stimulating brain NAD synthesis.

In addition, a 2012 study observed that mice fed a high-fat diet supplemented with nicotinamide riboside gained 60 percent less weight than mice fed the same high-fat diet without nicotinamide riboside.

Nicotinamide riboside chloride (3-aminoformyl-1 -[(2R, 3R, 4S5R)-3, 4-dihydroxy-5 -(hydroxymethyl) oxacyclopentane-2-yl] -pyridine-1-onium chloride; Also known as 1-(β-D-ribofuranyl) nicotinamide chloride) is a known salt form of nicotinamide riboside, which, despite the presence of useful properties of nicotinamide riboside and its chloride salts (for example in drugs or nutritional supplements), is generally in need of improvement.

Pharmacological action of nicotinamide riboside.

Product Method of Bulk nicotinamide riboside Powder.