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Chondroitin Sulfate Raw Materials Powder Chondroitin Sulfate
Product Overview:
chondroitinsulfate (CS) is an acid mucopolysaccharide extracted and purified from animal cartilage. Chondroitin sulfate has different structures such as A, C, D, E, H and K. Chondroitin sulfate in nature is mostly found in the cartilage, throat bone and nose bone of animals (41% in pigs), the diaphragm and trachea of cattle and horses (36% to 39% in pigs), and other tissues such as leg bones, ligaments, skin and corneas. The content of fish cartilage is very rich, such as shark bone contains 50% to 60%, and the content of connective tissue is very small
Chondroitin Sulfate Raw Materials Powder Chondroitin Sulfate Attributes
CAS:9007-28-7
MF:C13H21NO15S
MW:463.36854
EINECS:232-696-9
Specification: 99% min Chondroitin Sulfate Powder
Sample:Chondroitin Sulfate
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Chondroitin Sulfate Raw Materials Powder Chondroitin Sulfate Details
Chondroitin Sulfate Powder Usage and Synthesis.
1. Chondroitin sulfate, as a health food or health drug, has been used for a long time to prevent and treat coronary heart disease, angina pectoris, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases, without obvious toxic side effects, and can significantly reduce the morbidity and mortality of patients with coronary heart disease. Long-term clinical application has found that lipids such as fat deposited on the artery and vein walls can be effectively removed or reduced, which can significantly reduce plasma cholesterol, thereby preventing the formation of atherosclerosis.
2. Chondroitin sulfate is used to treat neuralgia, neuropathic migraine, joint pain, arthritis, scapular joint pain, abdominal pain and so on.
3. The prevention and treatment of hearing disorders caused by streptomycin and hearing difficulties caused by various noises, tinnitus and so on, the effect is remarkable.
4. It has adjuvant therapeutic effect on chronic nephritis, chronic hepatitis, keratitis and corneal ulcer.
5. In recent years, it has been reported that chondroitin in shark cartilage has anti-tumor effects. In addition, chondroitin sulfate is also used in cosmetics and wound healing agents.
6. Chondroitin sulfate is also used in eye drops.
Uses and functions of Chondroitin Sulfate.
1. Chondroitin sulfate is a mucopolysaccharide extracted from animal cartilage, which plays an important role in the prevention and treatment of cardiovascular diseases and joint diseases, and is the most important biochemical product on the market at present.
2. Chondroitin sulfate, as a health food or health drug, has been used for a long time in the prevention and treatment of coronary heart disease, angina pectoris, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases, without obvious toxic side effects, and can significantly reduce the morbidity and mortality of patients with coronary heart disease. Long-term clinical applications have found that lipids such as fat deposited on the walls of arteries and veins can be effectively removed or reduced to significantly lower plasma cholesterol, thereby preventing the formation of atherosclerosis.
3. Chondroitin sulfate is used to treat neuralgia, neuropathic migraine, joint pain, arthritis, scapular joint pain, abdominal abdominal surgery pain, etc.
4, the prevention and treatment of hearing disorders caused by streptomycin and various noise caused hearing difficulties, tinnitus, etc., the effect is significant.
5, chronic nephritis, chronic hepatitis, keratitis and corneal ulcer and other auxiliary treatment. 6. In recent years, it has been reported that chondroitin in shark cartilage has anti-tumor effects. In addition, chondroitin sulfate is also used in cosmetics and wound healing agents. Chondroitin sulfate is an acid mucosaccharide, which is one of the important components of eye tissue. It can promote corneal water metabolism and improve it. It is suitable for visual fatigue and dry eye.
Pharmacological action of Chondroitin Sulfate.
Chondroitin sulfate is widely present in human and animal cartilage tissues. Its medicinal preparations mainly contain two isomers, chondroitin sulfate A and chondroitin sulfate C, and the content of chondroitin sulfate is different in the cartilage of different species and ages.
Its pharmacological effects are as follows:
1, Chondroitin sulfate can remove lipids and lipoproteins in the blood in the body, remove cholesterol in the blood vessels around the heart, prevent atherosclerosis, and increase the conversion rate of lipids and fatty acids in the cell.
2, chondroitin sulfate can effectively prevent and treat coronary heart disease. It has anti-atherosclerotic and anti-atherosclerotic plaque formation effect on experimental arteriosclerosis model. Increases atherosclerotic coronary artery dissection or collateral circulation and accelerates healing, regeneration, and repair of myocardial necrosis or degeneration caused by experimental coronary atherosclerosis or embolization.
3, can increase the cell messenger ribonucleic acid (mRNA) and deoxyribonucleic acid (DNA) biosynthesis and has the role of promoting cell metabolism.
4. Low anticoagulant activity. Chondroitin sulfate has A mild anticoagulant effect, and every lmg Chondroitin sulfate A is equivalent to 0.45U of heparin. This anticoagulant activity does not depend on antithrombin III, it can exert anticoagulant activity through the fibrinogen system.
5, Chondroitin sulfate also has anti-inflammatory, accelerated wound healing and anti-tumor effects.
Product method of Bulk Chondroitin Sulfate Powder.
The pig's throat and nose cartilage were extracted with 2% sodium hydroxide, and the extracted liquid was hydrolyzed with crude pancreatic enzyme at 50℃ to remove impurities such as protein. Filtration, enzymatic hydrolysate to adjust pH to 6, adding ethanol to achieve 75% ethanol concentration. The precipitate obtained by centrifugation is chondroitin sulfate coarse product. The finished product is obtained by multi-step refining. The total yield was 5%.