Anti-infection Furazolidone Raw material powder on sale

CAS:67-45-8

MF:C17H21NO3

MW:287.35

EINECS:609-175-3

Specification: 99% min Furazolidone powder

Sample:Furazolidone powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: yellow

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Furazolidone Powder Usage and Synthesis.

Furazolidone is a nitrofuran antimicrobial. It has certain antibacterial effect on gram-positive and negative bacteria, including Salmonella, Shigella, Escherichia coli, Klebsiella pneumoniae, Enterobacteriaceae, Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes, Vibrio cholerae, Campylobacterium, Bacteroidetes, etc., and is also active against trichomoniasis and Giardia at a certain concentration. Its mechanism of action is to interfere with bacterial oxidoreductase, thereby blocking the normal metabolism of bacteria.

Uses of Furazolidone.

The antimicrobial spectrum is similar to that of nitrofurandidine, and has antibacterial effects on Salmonella, Shigella, Escherichia coli, Proteus, Streptococcus, and Staphylococcus. 

Bacteria are not easy to develop drug resistance to this product, and there is no cross-resistance with sulfonamides and antibiotics. Clinically, it is mainly used for bacillary dysentery, enteritis, typhoid fever, paratyphoid fever and external treatment of vaginal trichomoniasis, furazolidone is a fungicide, with a wide antibacterial spectrum, and the most sensitive bacteria are Escherichia coli, Bacillus anthracis, paratyphoid rod, dysentery bacillus, pneumonia bacillus, and typhoid bacillus are also sensitive. It is mainly used for bacterial dysentery, enteritis, cholera caused by sensitive bacteria, and can also be used for typhoid, paratyphoid, giardiasis, trichomoniasis, etc. 

Combined with drugs such as antacids can treat gastritis caused by Helicobacter pylori. Properties: yellow powder or crystalline powder, odorless, slightly bitter after initial tastelessness, very slightly soluble in water and ethanol, slightly soluble in chloroform, insoluble in ether, soluble in dimethylformamide and nitromethane, the product is a fungicide with a wide antibacterial spectrum. As an anti-infective drug, it is effective against a variety of gram-positive and negative Escherichia coli, anthrax, paratyphoid bacillus, etc., and is used for the treatment of bacillary dysentery, enteritis, vaginal infection, and in recent years, it has been used to treat typhoid fever with good efficacy. 

As an animal drug and beverage additive, it has a special antibacterial effect on Salmonella, such as chick dysentery and Escherichia coli, and also has a certain effect on protozoa (coccidiosis, etc.), and is not easy to appear drug resistance. Furazolidone is used in small quantities as a biocide in meta-based applications such as water-soluble coatings and pulp.

Pharmacological action of Furazolidone.

Product Method of Bulk Furazolidone Powder.

Ethanolamine was used as raw material, condensation with urea to obtain β-hydroxyethyl urea, and nitrosation and cyclization were used to obtain 3-nitroso-2-azolidinone. It is further reduced with iron powder, and then condensed with 5-nitro-2-furfurmandiol diacetate and formaldehyde to obtain furazolidone.