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Antimicrobial Faropenem sodium Raw Materials powder

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Product Overview:

Faropenem sodium is the first oral penem antibiotic on the market in China. It has a 4-hydrofuran group attached to the 2-position of the penem mother nucleus, and its chemical structure is relatively stable. Its basic structure is similar to that of β-lactam antibiotics, which belongs to the non-typical β-lactam antibiotics. It is a national Class four new drug developed by China. It has broad spectrum antibacterial activity, no less than temipenem and cilastatin sodium for injection; It has a wide antibacterial spectrum for aerobic gram-positive bacteria, aerobic Gram-negative bacteria and anaerobic bacteria. Especially for the aerobic gram-positive bacteria Staphylococcus, Moraxella, streptococcus, pneumococcus, enterococcus, aerobic gram-negative bacteria citrobacter, enterobacter, Klebsiella, Proteus, influenza bacteria, peptostreptococcus, propionibacterium, Bacillus haemophagosis pertussis and anaerobic bacteria in peptostreptococcus, bacteroides, etc., showing strong bactericidal efficacy. The antibacterial activity is better than that of existing oral cephalosporin antibiotics. It is the best choice for patients with severe infection in hospitals.

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Antimicrobial Faropenem sodium Raw Materials powder Attributes

Faropenem sodium Raw Materials powder

CAS:122547-49-3

MF:C12H14NO5S.Na

MW:307.3

EINECS:1592732-453-0

Specification: 99% min Faropenem sodium powder

Sample:Faropenem sodium powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Antimicrobial Faropenem sodium Raw Materials powder Details

Faropenem sodium powder Usage and Synthesis.

Antibacterial action

Faropenem sodium can inhibit staphylococcus, streptococcus and many gram-negative bacteria, including influenza bacillus, gonococcus, Lankatabhanella, has a strong biological activity. It is particularly effective against anaerobic bacteria, and its antibacterial effect in vitro has been compared with many antibiotics, such as cefteram, cefixime, cefaclor, amoxicillin, cefotaxime, cefuroxime, Clindamycin, imipenem, cefpoxime, ciprofloxacin, Piperacil, ametine, Metronidazole, tobramycin, vancomycin, etc. Its inhibition of anaerobic bacteria is stronger than that of the antibiotics in the trial, and it is by far the strongest antibiotic against anaerobic bacteria. In addition, it is more effective against staphylococcus, pneumococcus, streptococcus and many gram-negative bacteria than cefteram, cefixime, cefaclor, amoxicillin, and 5-10 times stronger than third-generation cephalosporins.

The MIC of this product against all clinically isolated bacteria was 0.78μg/ml, and it was much more effective against campylobacter than erythromycin, methythromycin, roxithromycin and ofloxacin. It is very effective in inhibiting streptococcus and Clostridium difficile, MIC90≤1μg/ml; Bacteroides fragilis MIC90≤4μg/ml. Antibacterial effect is not affected by food, this product has bactericidal effect.

Uses and functions of Faropenem sodium.

Faropenem is a fully synthetic penicillin antibiotic with wide antibacterial spectrum and strong antibacterial activity. It has become an important therapeutic drug for serious bacterial infections and can be used to treat infections caused by sensitive gram-positive bacteria, gram-negative bacteria and anaerobic bacteria. It is stable to various lactamases and also stable to renal dehydropeptidase-I.

Faropenem sodium

Indication of Faropenem sodium.

Faropenem sodium is mainly used to treat the following infectious diseases caused by staphylococcus, streptococcus, pneumococcus, Enterococcus, Moraxella cataraxia, Escherichia coli, Citrobacter, Klebsiella, Enterobacter mirabilis, Haemophilus influenzae, peptostreptococcus, propionibacterium acnes, Bacteroides and other sensitive bacteria:

1. Urinary system infection: pyelonephritis, cystitis, prostatitis, orchitis;

2. Respiratory system infection: pharyngitis, tonsillitis, acute and chronic bronchitis, pneumonia, lung abscess (pulmonary abscess);

3. Adjunctitis of uterus, intrauterine infection, bartylitis of vestibular gland;

4. Superficial skin infections, deep skin infections, acne (accompanied by suppurative inflammation); 5. Secondary infections such as lymphangitis, lymphadenitis, mastitis, perianal abscess, trauma, scalding and surgical trauma;

6. Dacryocystitis, stye, meibomian adenitis, keratitis (including corneal ulcer);

7. Otitis externa, otitis media, sinusitis;

8, periodontitis, periodontitis, jaw inflammation.

In clinical use, especially for pediatric bacterial infections, such as respiratory tract infections, 95-100% effective, high clinical evaluation.

In China, Faropenem belongs to the third-line antibacterial drugs, which are generally used to treat drug-resistant bacteria or mixed infections of multiple bacteria, or will be used when other antibacterial drugs are ineffective or cannot be used.

Faropenem sodium raw