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Cefotaxime sodium Raw material powder
Product Overview:
Cefotaxime sodium is a commonly used carbapenem antibiotic, belonging to the third generation of semi-synthetic cephalosporin, with a wider antibacterial spectrum than cefuroxime and stronger effect on gram-negative bacteria. The antibacterial spectrum includes enterobacteriaceae bacteria such as Haemophilus influenzae, Escherichia coli, Escherichia coli, Salmonella, Klebsiella and Proteus mirabilis, Neisseria, Staphylococcus, Pneumococcus, Streptococcus, Klebsiella and Salmonella. Cefotaxime sodium has no antibacterial activity against Pseudomonas aeruginosa and alcaligenes, poor antibacterial activity against Staphylococcus aureus, strong activity against hemolytic streptococcus, Streptococcus pneumoniae and other gram-positive bacteria, enterococcus (Enterobacter cloacae, Enterobacter aerogenes) resistance to this product.
Cefotaxime sodium Raw material powder Attributes
CAS:64485-93-4
MF:C16H18N5NaO7S2
MW:298.43479.46
EINECS:264-915-9
Specification: 99% min Cefotaxime sodium powder
Sample:Cefotaxime sodium powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance: white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Cefotaxime sodium Raw material powder Details
Cefotaxime sodium Powder Usage and Synthesis.
Cefotaxime sodium can be used clinically for pneumonia and other lower respiratory tract infections, urinary tract infections, meningitis, septicemia, abdominal infection, pelvic infection, skin and soft tissue infection, reproductive tract infection, bone and joint infection caused by sensitive bacteria. Cefotaxime can be used as the drug of choice in children with meningitis.
Uses of Cefotaxime sodium.
The third generation of broad spectrum cephalosporin antibiotics have strong bactericidal effect on gram-negative and positive bacteria, especially on gram-negative bacteria, stable to β-lactamase, and need to be injected. It is clinically used for respiratory system infection, urinary system infection, biliary tract and intestinal infection, skin and soft tissue infection, septicemia, burn and bone and joint infection caused by sensitive bacteria. It is mainly used to treat respiratory system, urinary system, intestinal tract and biliary tract, skin and soft tissue, burn and bone and joint infection caused by sensitive bacteria.
In vitro study of Cefotaxime sodium.
Product Method of Bulk Cefotaxime sodium Powder.
8g sodium bicarbonate dissolved in 20ml ethanol, 45.55g 3-acetoxymethyl-7 -[2-(2-amino-4-thiazolyl) -2-methoxyiminoacetamido] ceftaxime slightly 4-carboxylic acid (Cefotaxime) dissolved in 100ml distilled water was continuously added, then 80rnl ethanol and 4.5g activated carbon were added. Stir for 5 minutes and strain. Wash the cake with ethanol, concentrate the filtrate under reduced pressure, and dissolve the remaining in: 100ml ethanol, then concentrate until dry. The remainder was dissolved in 100ml methanol and poured into 2L acetone. The solution was stirred violently and filtered under reduced pressure. The solid was washed with acetone and then with ether, and dried under vacuum. 43.7g white cefotaxime sodium was obtained. The cefotaxime sodium is hygrometric in air, and the weight after hygrometric is 45.2g, which is the hydrate of cefotaxime sodium.
