Nutritional Supplements methylcobalamin Raw Materials powder

CAS:13422-55-4

MF:C38H69NO13

MW:747.95

EINECS:1806241-263-5

Specification​: 99% min methylcobalamin powder

Sample:methylcobalamin powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:red

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

methylcobalamin powder Usage and Synthesis.

Mecobalamine is a therapeutic drug for peripheral nerve disorders. Compared with other vitamin B12 preparations, mecobalamine has good transmission to nerve tissue. It can promote nucleic acid-protein-lipid metabolism through methyl-conversion reaction and repair damaged nerve tissue. It plays the role of coenzyme in the synthesis of methionine from homocysteine, especially participating in the synthesis of thymine nucleoside from deoxyuracil nucleoside, promoting the synthesis of DNA and RNA. In addition, in the experiment of glial cells, the drug increased the activity of methionine synthetase and promoted the synthesis of myelin lipid lecithin. Improving the metabolic disorders of nerve tissue can promote the synthesis of axons and their proteins, make the transport rate of bone protein close to normal, and maintain the function of axons.

Uses of methylcobalamin.

Mecobalamine is an endogenous coB12 that participates in the one carbon unit cycle and plays an important role in the transmethylation of methionine from homocysteine. It is used to treat neurological diseases, relieve pain and numbness, quickly relieve neuralgia, improve the pain caused by cervical spondylosis, and treat sudden deafness.

Pharmacological action of methylcobalamin.

Mecobalamine, a derivative of vitamin B12, is named by its chemical structure and should be called "methylvitamin B12". Its methylated functional groups can participate in the methyl transfer activity in the biochemical process of the body, promote the metabolism of nucleic acid, protein and fat in nerve tissue, stimulate lecithin synthesis in Schwann cells, repair the damaged myelin sheath, and improve nerve conduction speed. It can directly enter the nerve cells and stimulate the regeneration of the damaged axon area; Stimulate the protein synthesis of nerve cells, strengthen the anabolism of axons, prevent axonal degeneration; Participate in nucleic acid synthesis, promote hematopoietic function. It is often used in the treatment of diabetic neuropathy, and long-term use has a certain effect on the large vascular complications of diabetes. Mecobalamine is mainly used for peripheral nerve diseases caused by diabetes and megaloblastic anemia caused by vitamin B12 deficiency, which is widely used in clinical practice with few side effects.

Product method of Bulk methylcobalamin.