Raw materials for medical and health care products yohimbine

CAS:146-48-5

MF:C21H26N2O3

MW:354.44

EINECS:205-672-0

Specification​: 99% min yohimbine Powder

Sample:yohimbine Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

yohimbine Powder Usage and Synthesis.

It is suitable for the treatment of psychological erectile dysfunction, but has poor effect on organic erectile dysfunction. Yohimbine is the first prescription drug approved by the FDA to treat impotence, and its main effect comes from blocking the alpha2adrenergic receptor on the central nervous system, which can dilate blood vessels around the genital organs, causing complete congestion to solve the problem of erectile dysfunction. In 1987, 34% to 43% of users benefited from the clinical trial. Yohimbine pure white powder, slightly soluble in water, soluble in ethanol, chloroform, hot benzene, slightly soluble in ether.

Uses of yohimbine.

It has adrenergic blocking effect and is used in the treatment of arteriosclerosis and angina pectoris. It has been used in the past as a local anesthetic and mydriatic, and seems to have an aphrodisiac effect.

Pharmacological action of yohimbine.

Yohimbine can selectively block the presynaptic α2 receptor and promote the release of supradrenal adenin. It makes the cavernosal nerve endings release more norepinephrine supradrenal gland, reduce penile venous reflux, conducive to congestion erection. A small amount of application, can make the perineum swelling, stimulate the spinal erectile center and make sexual hyperfunction. Yohimbine hydrochloride can also produce psychological excitatory effect, increase sexual desire.

① When used in a small amount, it acts on the erectile center of the lumbar spine, and promotes sexual hyperfunction.

② It has adrenergic blocking effect. Clinical application: Used for functional impotence caused by neurasthenia, but also for secondary impotence caused by diabetes. Oral dose: 0.005 ~ 0.01g, 3 times a day. Severe patients were subcutaneously injected with 2% yohimbine solution 0.5 ~ 1.0ml, 2 ~ 3 times a day, with a course of 20 times. Side toxic reaction: It has a local anesthetic effect similar to cocaine, and occasionally has palpitations, insomnia, vertigo and other diseases. It can be relieved when the drug is stopped. Clinical preparations: Yohimbine hydrochloride and compound preparations commonly used abroad containing yohimbine, Yosidol's yohimbine, Buloch's yohimbine tablet, Diphoyohimbine, Gushi's yohimbine, Khohimbine's Yohimbine, Knoryohimbine tablet, Yosteline, Yurbinin, Maclobin, tonotan, etc. In addition, similar alkaloids are commonly used in corynanthin and capella.

Product Method of Bulk yohimbine Powder.