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Fluoxetine hydrochloride Raw Materials Powder
Product Overview:
Fluoxetine hydrochloride is the world's first listed selective serotonin reuptake inhibitors (SSRIs) antidepressant drug, the product name "Prozac" (Prozac), by the United States Eli Lilly Company first developed successfully. Fluoxetine is the first antidepressant in the 5-HT reuptake inhibitor class to be marketed, which has different structure and pharmacological mechanism from previous TCAs antidepressants. Its curative effect is exact, side effects are light, after the market is favored, sales have increased significantly year by year. Since the development of fluoxetine by Eli Lilly in the 1970s, it has created a lot of glory and can be called a generation of legends, opening up a new chapter in the treatment of depression. Although the market has declined since 2001, it is still one of the most commonly used drugs for antidepressant treatment.
Fluoxetine hydrochloride Raw Materials Powder Attributes
CAS:56296-78-7
MF:C17H19ClF3NO
MW:345.79
EINECS:260-101-2
Specification: 99% min Fluoxetine hydrochloride Powder
Sample:Fluoxetine hydrochloride
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Fluoxetine hydrochloride Raw Materials Powder Details
Fluoxetine hydrochloride Powder Usage and Synthesis.
Fluoxetine hydrochloride can be used for all types of depression, especially for organic diseases accompanied by depressive symptoms and senile depression. It is also used to treat post-schizophrenic depression. It is also used for obsessive-compulsive disorder, phobia, anxiety symptoms of depression, bulimia nervosa, weight loss and as an adjunct to smoking cessation.
Uses and functions of Fluoxetine hydrochloride.
Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI) for the treatment of a variety of depressive mental disorders, including minor or major depression, bipolar affective disorder depression, psychogenic depression, and depressive neurosis. The mechanism of action is to inhibit the uptake of serotonin by neurons from the synaptic gap, increasing the availability of this neurotransmitter in the gap, thereby improving emotional states and treating depressive mental disorders. Common adverse reactions were dry mouth, loss of appetite, nausea, insomnia, fatigue, and anxiety and headache in a few cases. Due to the long half-life of fluoxetine hydrochloride, the dose should be appropriately reduced in patients with poor liver and kidney function or elderly patients. Children should follow the doctor's advice when using. Use with caution in people with a history of epilepsy, pregnant or lactating women. If rash or fever occurs, stop taking the medicine immediately and treat the symptoms. It should not be combined with monoamine oxidase inhibitors (MAOI). If necessary, this drug should be discontinued for 5 weeks before switching to monoamine oxidase inhibitors (MAOI).
Pharmacological action of Fluoxetine hydrochloride.
Fluoxetine blocks the 5-HT2A receptor and restores DA and NE levels by inhibiting the 5-HT2A receptor. At the same time, fluoxetine can also relieve the inhibition of NE and DA release by GABA neurons through 5-HT2C receptor. In addition to increasing the concentration of 5-HT in the synaptic cleft, it is based on fluoxetine's effect on 5-HT2A and 5-HT2C that the levels of DA and NE are directly and indirectly restored, with NE and DA deinhibition properties (NDDI).
Product method of Bulk Fluoxetine hydrochloride Powder.
