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Raw Materials powder Sulfaguanidine
Product Overview:
Sulfanilamide and sulfanidine were once commonly used varieties of sulfanilamide drugs, because of their greater toxicity, they are generally not used as the drug of choice, and now they and acetaminobenzene sulfonyl chloride are only used as intermediates in the production of sulfanilamide drugs. Sulfanidine, also known as sulfanidine, stop dysentery tablets, the earliest for intestinal infection of sulfanidine drug, sulfanidine molecular structure has a strong basic guanidine, large dissociation, fat solubility is small, although there is a certain amount of absorption from the intestine after internal administration, but not enough to achieve effective blood concentration, so it is not used for systemic infection. However, it can maintain a high concentration in the intestine and is mostly used for bacterial infections of the digestive tract. Such as gastroenteritis, dysentery, etc.
Raw Materials powder Sulfaguanidine Attributes
CAS:57-67-0
MF:C7H10N4O2S
MW:214.24
EINECS:200-345-9
Specification: 99% min Sulfaguanidine powder
Sample:Sulfaguanidine powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Raw Materials powder Sulfaguanidine Details
Sulfaguanidine powder Usage and Synthesis.
1, at the same time, the application of urine alkalization drugs can enhance the solubility of this product in alkaline urine and increase excretion.
2, sulfanidine can not be used with p-aminobenzoic acid, p-aminobenzoic acid can be taken up by bacteria instead of this product, and the two are antagonistic. It should not be used with para-benzoyl-containing local anesthetics such as procaine, tetracaine, etc.
3, for those who take estrogen contraceptives, the long-term application of sulfamidine can lead to a reduction in the reliability of contraception and increase the chance of menstrual bleeding.
4, photosensitive additive effect may occur when combined with photosensitive drugs.
5, the need for vitamin K increased in those treated with this product.
Uses of Sulfaguanidine.
Sulfamidine is a lower form of the sulfanilamide family that inhibits bacteria. It is mainly used for the production of sulfadiazine, sulfadiazine and other advanced sulfonamides.
The drug of choice for the treatment of leprosy is suitable for the treatment of all types of leprosy and can improve clinical symptoms. The general mucosal lesions improve faster, the skin lesions improve more slowly, neuropathy is slower, so the course of treatment is long, easy to produce drug resistance, not easy to cure, in addition, can also be used to treat dermatitis herpetiformis, lupus erythematosus, psoriasis, podiomycosis and malaria. The preparation is in tablet form.
Pharmacological action of Sulfaguanidine.
Product method of Bulk Sulfaguanidine.
